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2019 WSES guidelines for the management of severe acute pancreatitis.

Published version
Peer-reviewed

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Authors

Leppäniemi, Ari 
Tolonen, Matti 
Tarasconi, Antonio 
Segovia-Lohse, Helmut 
Gamberini, Emiliano 

Abstract

Although most patients with acute pancreatitis have the mild form of the disease, about 20-30% develops a severe form, often associated with single or multiple organ dysfunction requiring intensive care. Identifying the severe form early is one of the major challenges in managing severe acute pancreatitis. Infection of the pancreatic and peripancreatic necrosis occurs in about 20-40% of patients with severe acute pancreatitis, and is associated with worsening organ dysfunctions. While most patients with sterile necrosis can be managed nonoperatively, patients with infected necrosis usually require an intervention that can be percutaneous, endoscopic, or open surgical. These guidelines present evidence-based international consensus statements on the management of severe acute pancreatitis from collaboration of a panel of experts meeting during the World Congress of Emergency Surgery in June 27-30, 2018 in Bertinoro, Italy. The main topics of these guidelines fall under the following topics: Diagnosis, Antibiotic treatment, Management in the Intensive Care Unit, Surgical and operative management, and Open abdomen.

Description

Keywords

Acute pancreatitis, Consensus statement, Infected necrosis, Necrosectomy, Open abdomen, Acute Disease, Amylases, Anti-Bacterial Agents, C-Reactive Protein, Endoscopy, Guidelines as Topic, Hematocrit, Humans, Italy, Lipase, Pancreatitis, Procalcitonin, Tomography, X-Ray Computed, Treatment Outcome, Ultrasonography

Journal Title

World J Emerg Surg

Conference Name

Journal ISSN

1749-7922
1749-7922

Volume Title

14

Publisher

Springer Science and Business Media LLC