The last wall of defence to prevent extreme and deleterious mitochondrial fusion


Type
Article
Change log
Authors
Tabara, Luis Carlos 
Abstract

Mitochondrial are dynamic organelles adapting their morphology by cycles of fission and fusion events to control cellular homeostasis. In this issue of The EMBO journal, Murata and colleagues (2020) show that lack of mitochondrial division leads to safeguard mechanisms, induced by transient mitochondrial membrane depolarisation and activation of the metalloprotease OMA1, to prevent extreme mitochondrial fusion and to maintain optimal mitochondrial bioenergetics.

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Keywords
Journal Title
The EMBO Journal
Conference Name
Journal ISSN
0261-4189
Volume Title
Publisher
EMBO Press
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Rights
All rights reserved