The wasting hormone GDF15 frees up fat to fight infection.


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Type
Article
Change log
Authors
Lockhart, Samuel M 
Abstract

GDF15 is an anorectic hormone that signals organismal stress to the brain. New data suggest that GDF15 enhances tolerance in acute inflammation by modulating liver lipid metabolism and triglyceride availability in mice.

Description
Keywords
32 Biomedical and Clinical Sciences, 3202 Clinical Sciences, 3 Good Health and Well Being
Journal Title
Nat Metab
Conference Name
Journal ISSN
2522-5812
2522-5812
Volume Title
1
Publisher
Springer Science and Business Media LLC
Rights
All rights reserved
Sponsorship
Cambridge University Hospitals NHS Foundation Trust (CUH) (146281)
MRC (Unknown)
Wellcome Trust (214274/Z/18/Z)
Medical Research Council (MC_UU_12012/1)
MRC (MC_UU_00014/1)
WT/NIHR