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The wasting hormone GDF15 frees up fat to fight infection.

Accepted version
Peer-reviewed

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Type

Article

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Authors

Lockhart, Samuel M 

Abstract

GDF15 is an anorectic hormone that signals organismal stress to the brain. New data suggest that GDF15 enhances tolerance in acute inflammation by modulating liver lipid metabolism and triglyceride availability in mice.

Description

Keywords

32 Biomedical and Clinical Sciences, 3202 Clinical Sciences, Digestive Diseases, Neurosciences, Liver Disease, Nutrition, 2.1 Biological and endogenous factors, 3 Good Health and Well Being

Journal Title

Nat Metab

Conference Name

Journal ISSN

2522-5812
2522-5812

Volume Title

1

Publisher

Springer Science and Business Media LLC

Rights

All rights reserved
Sponsorship
Cambridge University Hospitals NHS Foundation Trust (CUH) (146281)
MRC (Unknown)
Wellcome Trust (214274/Z/18/Z)
Medical Research Council (MC_UU_12012/1)
MRC (MC_UU_00014/1)
Medical Research Council (MC_PC_12012)
WT/NIHR