Non-Genetic Transmission of Obesity - It's in Your Epigenes.

Accepted version
Repository DOI

Type
Article
Change log
Authors
Loche, Elena 
Ozanne, Susan E 
Abstract

Obesity and its related metabolic comorbidities can be inherited across generations through non-genetic mechanisms. In a recent report, Huypens et al., using an in vitro fertilization approach, provide evidence that exposure to a high-fat diet modifies egg and sperm epigenetic information, rendering the progeny more prone to obesity.

Description
Keywords
Diet, High-Fat, Epigenesis, Genetic, Female, Humans, Male, Maternal Exposure, Obesity, Paternal Exposure
Journal Title
Trends Endocrinol Metab
Conference Name
Journal ISSN
1043-2760
1879-3061
Volume Title
Publisher
Elsevier BV
Sponsorship
Medical Research Council (MC_UU_12012/4)
Biotechnology and Biological Sciences Research Council (BB/M001636/1)
British Heart Foundation (None)
British Heart Foundation (None)
Our research is supported by the MRC (MC_UU_12012/4) and the British Heart Foundation (FS/12/64/30001 and PG/14/20/30769).