Birth cohort-specific trends of sun-related behaviors among individuals from an international consortium of melanoma-prone families.


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Authors
Lacson, John Charles A 
Zamani, Shawn A 
Froes, Luis Alberto Ribeiro  ORCID logo  https://orcid.org/0000-0002-1140-3046
Mitra, Nandita 
Qian, Lu 
Abstract

BACKGROUND: Individuals from melanoma-prone families have similar or reduced sun-protective behaviors compared to the general population. Studies on trends in sun-related behaviors have been temporally and geographically limited. METHODS: Individuals from an international consortium of melanoma-prone families (GenoMEL) were retrospectively asked about sunscreen use, sun exposure (time spent outside), sunburns, and sunbed use at several timepoints over their lifetime. Generalized linear mixed models were used to examine the association between these outcomes and birth cohort defined by decade spans, after adjusting for covariates. RESULTS: A total of 2407 participants from 547 families across 17 centers were analyzed. Sunscreen use increased across subsequent birth cohorts, and although the likelihood of sunburns increased until the 1950s birth cohort, it decreased thereafter. Average sun exposure did not change across the birth cohorts, and the likelihood of sunbed use increased in more recent birth cohorts. We generally did not find any differences in sun-related behavior when comparing melanoma cases to non-cases. Melanoma cases had increased sunscreen use, decreased sun exposure, and decreased odds of sunburn and sunbed use after melanoma diagnosis compared to before diagnosis. CONCLUSIONS: Although sunscreen use has increased and the likelihood of sunburns has decreased in more recent birth cohorts, individuals in melanoma-prone families have not reduced their overall sun exposure and had an increased likelihood of sunbed use in more recent birth cohorts. These observations demonstrate partial improvements in melanoma prevention and suggest that additional intervention strategies may be needed to achieve optimal sun-protective behavior in melanoma-prone families.

Description

Funder: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; doi: http://dx.doi.org/10.13039/501100002322


Funder: Radiumhemmets Forskningsfonder; doi: http://dx.doi.org/10.13039/501100007232


Funder: Swedish Cancer Society


Funder: Lunds Universitet Paulsson Trust


Funder: CIBER de Enfermedades Raras of the Instituto de Salud Carlos III


Funder: European Regional Development Fund; doi: http://dx.doi.org/10.13039/501100008530


Funder: Diagnoptics


Funder: CERCA Programme Generalitat de Catalunya


Funder: Esther Koplowitz Center, Barcelona, Spain


Funder: Comision Honoraria de Lucha Contra el Cancer, CSIC, Fundacion Manuel Perez, Montevideo, Uruguay

Keywords
High-risk families, Melanoma, Skin Cancer, Sun exposure, Sun-related behaviors, Sunbed, Sunburn, Sunscreen use, Trends, Humans, Melanoma, Retrospective Studies, Skin Neoplasms, Sunburn, Sunscreening Agents
Journal Title
BMC Public Health
Conference Name
Journal ISSN
1471-2458
1471-2458
Volume Title
21
Publisher
Springer Science and Business Media LLC
Sponsorship
Sixth Framework Programme (LSH-CT-2006-018702)
Cancer Research UK Programme Award (C588/A4994, C588/ A10589)
United Kingdom Clinical Research Collaboration (GB) (C8216/A6129)
National Institutes of Health (R01 CA83115)
National Health and Medical Research Council of Australia (NHMRC 107359, 402761, 633004, 566946, 211172, 1093017, 1147843)
Cancer Council NSW (project grant 77/00, 06/10)
Cancer Institute NSW (CINSW 05/TPG/1-01, 10/TPG/1-02], 15/CDF/1-14)
Fundação de Amparo à Pesquisa do Estado de São Paulo (2007/04313-2)
H2020 European Research Council () (ERC-2011-294576)
Spanish Fondo de Investigaciones Sanitarias (PI15/00716, PI15/00956)
Catalan Government, Spain (AGAUR 2014_SGR_603)
Fundació la Marató de TV3 (201331-30)
Fundación Científica Asociación Española Contra el Cáncer (GCB15152978SOEN)
Italian Ministry of Health (RF-2016-02362288)
Consejo Nacional de Ciencia y Tecnología (152256/158706)