Structural equation model for estimating risk factors in type 2 diabetes mellitus in a Middle Eastern setting: evidence from the STEPS Qatar.
| cam.issuedOnline | 2016-09-29 | |
| dc.contributor.author | Roman-Urrestarazu, Andres | |
| dc.contributor.author | Ali, Faleh Mohamed Hussain | |
| dc.contributor.author | Reka, Husein | |
| dc.contributor.author | Renwick, Matthew J | |
| dc.contributor.author | Roman, Gabriela D | |
| dc.contributor.author | Mossialos, Elias | |
| dc.contributor.orcid | Roman-Urrestarazu, Andres [0000-0002-2405-9432] | |
| dc.date.accessioned | 2018-11-05T10:26:07Z | |
| dc.date.available | 2018-11-05T10:26:07Z | |
| dc.date.issued | 2016 | |
| dc.description.abstract | AIMS: Understanding type 2 diabetes mellitus is critical for designing effective diabetes prevention policies in Qatar and the Middle East. METHODS: Using the Qatar 2012 WHO STEPwise approach to surveillance survey, a subsample of 1224 Qatari participants aged 18-64 years was selected. Subjects had their fasting blood glucose levels tested, had not been diagnosed with or treated for diabetes, had a fasting time >12 hours and were not pregnant. We applied a hypothesized structural equation model (SEM) to assess sociodemographic, behavioral, anthropometric and metabolic variables affecting persons with type 2 diabetes mellitus. RESULTS: There is a direct effect of triglyceride levels (0.336) and body mass index (BMI) (0.164) on diabetes status. We also found that physical activity levels negatively affect BMI (-0.148) and positively affect high-density lipoprotein (HDL) (0.106); sociodemographic background negatively affects diet (-0.522) and BMI (-0.352); HDL positively affects total cholesterol (0.230) and has a negative effect on BMI (-0.108), triglycerides (-0.128) and waist circumference (-0.104). Diet has a positive effect on triglycerides (0.281) while family history of diabetes negatively affects total cholesterol (-0.104). BMI has a positive effect on waist circumference (0.788) and mediates the effects of physical activity over diabetes status (-0.028). BMI also mediates the effects that sociodemographic factors (-0.058) and physical activity (-0.024) have on diabetes status. BMI and HDL (-0.002) together mediate the effect of physical activity on diabetes status and similarly HDL and tryglycerides (-0.005) also mediate the effect of physical activity on diabetes status. Finally diet and tryglycerides mediate the effects that sociodemographic factors have on diabetes status (-0.049). CONCLUSIONS: This study's main finding is that triglyceride levels and BMI are the main variables directly affecting diabetes status in the Qatari population. | |
| dc.format.medium | Electronic-eCollection | |
| dc.identifier.doi | 10.17863/CAM.31986 | |
| dc.identifier.eissn | 2052-4897 | |
| dc.identifier.issn | 2052-4897 | |
| dc.identifier.uri | https://www.repository.cam.ac.uk/handle/1810/284612 | |
| dc.language | eng | |
| dc.language.iso | eng | |
| dc.publisher | BMJ | |
| dc.publisher.url | http://dx.doi.org/10.1136/bmjdrc-2016-000231 | |
| dc.rights | Attribution-NonCommercial 4.0 International | |
| dc.rights.uri | https://creativecommons.org/licenses/by-nc/4.0/ | |
| dc.subject | Analytic Methods | |
| dc.subject | BMI | |
| dc.subject | Lipids and Diabetes | |
| dc.subject | Triglycerides | |
| dc.title | Structural equation model for estimating risk factors in type 2 diabetes mellitus in a Middle Eastern setting: evidence from the STEPS Qatar. | |
| dc.type | Article | |
| dcterms.dateAccepted | 2016-07-21 | |
| prism.issueIdentifier | 1 | |
| prism.publicationDate | 2016 | |
| prism.publicationName | BMJ Open Diabetes Res Care | |
| prism.startingPage | e000231 | |
| prism.volume | 4 | |
| pubs.funder-project-id | Gillings Family Foundation | |
| rioxxterms.licenseref.startdate | 2016-01 | |
| rioxxterms.licenseref.uri | http://www.rioxx.net/licenses/all-rights-reserved | |
| rioxxterms.type | Journal Article/Review | |
| rioxxterms.version | VoR | |
| rioxxterms.versionofrecord | 10.1136/bmjdrc-2016-000231 |
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