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Practicable assessment of cochlear size and shape from clinical CT images

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Gee, Andrew H. 
Zhao, Yufeng 
Treece, Graham M. 
Bance, Manohar L. 


Abstract: There is considerable interpersonal variation in the size and shape of the human cochlea, with evident consequences for cochlear implantation. The ability to characterize a specific cochlea, from preoperative computed tomography (CT) images, would allow the clinician to personalize the choice of electrode, surgical approach and postoperative programming. In this study, we present a fast, practicable and freely available method for estimating cochlear size and shape from clinical CT. The approach taken is to fit a template surface to the CT data, using either a statistical shape model or a locally affine deformation (LAD). After fitting, we measure cochlear size, duct length and a novel measure of basal turn non-planarity, which we suggest might correlate with the risk of insertion trauma. Gold-standard measurements from a convenience sample of 18 micro-CT scans are compared with the same quantities estimated from low-resolution, noisy, pseudo-clinical data synthesized from the same micro-CT scans. The best results were obtained using the LAD method, with an expected error of 8–17% of the gold-standard sample range for non-planarity, cochlear size and duct length.



Article, /639/166/985, /692/700/1421/2770, /692/700/1421/2025, /692/700/1421/1846, /692/698/1671/63, article

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Scientific Reports

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Nature Publishing Group UK
Medical Research Council (RG84584)
Evelyn Trust (RG9555)
Cambridge Hearing Trust (RG95594)