HumanMine: advanced data searching, analysis and cross-species comparison.


Type
Article
Change log
Authors
Bazaga, Adrián 
Butano, Daniela 
Contrino, Sergio 
Heimbach, Joshua 
Abstract

HumanMine (www.humanmine.org) is an integrated database of human genomics and proteomics data that provides a powerful interface to support sophisticated exploration and analysis of data compiled from experimental, computational and curated data sources. Built using the InterMine data integration platform, HumanMine includes genes, proteins, pathways, expression levels, Single nucleotide polymorphism (SNP), diseases and more, integrated into a single searchable database. HumanMine promotes integrative analysis, a powerful approach in modern biology that allows many sources of evidence to be analysed together. The data can be accessed through a user-friendly web interface as well as a powerful, scriptable web service Application programming interface (API) to allow programmatic access to data. The web interface includes a useful identifier resolution system, sophisticated query options and interactive results tables that enable powerful exploration of data, including data summaries, filtering, browsing and export. A set of graphical analysis tools provide a rich environment for data exploration including statistical enrichment of sets of genes or other biological entities. HumanMine can be used for integrative multistaged analysis that can lead to new insights and uncover previously unknown relationships. Database URL: https://www.humanmine.org.

Description
Keywords
database, bioinformatics
Journal Title
Database (Oxford)
Conference Name
Journal ISSN
1758-0463
1758-0463
Volume Title
Publisher
Oxford University Press (OUP)
Sponsorship
Wellcome Trust (099133/Z/12/Z)
Wellcome Trust (208381/Z/17/B)