This dataset (one excel file with multiple sheets) contains all the necessary data used to produce Figure 1 and Figure 4 to 10 in our manuscript. It contains the fibre attenuation and Raman gain spectrum used in the physical layer for Figure 1; hyperparameter optimisation, training, and validation data for the proposed DNN for Figure 4; performance evaluation of 3 approaches mentioned in the manuscript for Figure 5; optimal launch power profiles by PSO and the corresponding SNR profiles for Figure 6; Flat target SNR profiles and the desired launch power profiles for Figure 7; Parameter optimisation for the proposed greedy algorithm for Figure 8; optimal launch power profiles by the greedy algorithm and the corresponding SNR profiles for Figure 9; and achieved throughput and computational time of all approaches for Figure 10.