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Brief Report: The Go/No-Go Task Online: Inhibitory Control Deficits in Autism in a Large Sample.

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Uzefovsky, F 
Smith, P 


Autism Spectrum Conditions (ASC, also referred to as Autism Spectrum Disorders) entail difficulties with inhibition: inhibiting action, inhibiting one's own point of view, and inhibiting distractions that may interfere with a response set. However, the association between inhibitory control (IC) and ASC, especially in adulthood, is unclear. The current study measured IC, using the Go/No-Go task online, in a large adult sample of 201 people with ASC and 240 controls. Number of both False Alarm and False Positive responses were significantly associated with autistic traits and diagnostic status, separately, but not jointly. These findings suggest that deficits in inhibition are associated with ASC. Future studies need to investigate the role of inhibition in ASC in everyday difficulties.



Autism, Autism Spectrum Quotient, Go/No-Go, Inhibitory control, Adult, Autistic Disorder, Female, Humans, Inhibition, Psychological, Internet, Male, Middle Aged, Photic Stimulation, Psychomotor Performance, Reaction Time, Self Report

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Journal of Autism and Developmental Disorders

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Springer Nature
Medical Research Council (G0600977)
National Institute for Health Research (NIHR) (via Cambridgeshire and Peterborough NHS Foundation Trust (CPFT) (unknown)
European Commission and European Federation of Pharmaceutical Industries and Associations (EFPIA) FP7 Innovative Medicines Initiative (IMI) (115300)
This research was supported by the Autism Research Trust, the Medical Research Council (MRC) and EU-AIMS. FU was supported by the British Friends of Haifa University, the Israel Science Foundation (Grant No. 449/14), the British Friends of Hebrew University, and the Joseph Levy Charitable Foundation