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Structural and molecular basis of the epistasis effect in enhanced affinity between SARS-CoV-2 KP.3 and ACE2

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Peer-reviewed

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https://www.repository.cam.ac.uk/handle/1810/376946

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Authors

Jian, Fanchong  ORCID logo  https://orcid.org/0000-0001-8703-3507
Yang, Sijie  ORCID logo  https://orcid.org/0009-0001-9834-4340

Description

Acknowledgements: We express our gratitude to Drs. Boling Zhu, Xujing Li, and Lihong Chen for their valuable contribution to Cryo-EM data collection at the Center for Biological Imaging (CBI) of the Institute of Biophysics. This work was supported by the Ministry of Science and Technology of China (2021D0102, CPL-1233 and SRPG22-003), the National Key R&D Program (2023YFC3041500, 2023YFC3043200, 2023YFC2306000 and 2018YFA0900801), CAS (YSBR-010) and the National Science Foundation Grants (12034006, 32325004 and T2394482). Yunlong Cao was supported by the National Science Fund for Excellent Young Scholars (32222030). Xiangxi Wang was supported by the National Science Fund for Distinguished Young Scholar (32325004) and the NSFS Innovative Research Group (81921005).

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Springer Nature Singapore

Publisher DOI

https://doi.org/10.1038/s41421-024-00752-2

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Except where otherwised noted, this item's license is described as http://creativecommons.org/licenses/by/4.0/
Sponsorship
Ministry of Science and Technology of the People's Republic of China (Chinese Ministry of Science and Technology) (2021D0102)
National Natural Science Foundation of China (National Science Foundation of China) (12034006, 32325004, T2394482, 32325004, 81921005)

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