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The genetics of an early Neolithic pastoralist from the Zagros, Iran.

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cam.issuedOnline2016-08-09
dc.contributor.authorGallego-Llorente, M
dc.contributor.authorConnell, S
dc.contributor.authorJones, ER
dc.contributor.authorMerrett, DC
dc.contributor.authorJeon, Y
dc.contributor.authorEriksson, A
dc.contributor.authorSiska, V
dc.contributor.authorGamba, C
dc.contributor.authorMeiklejohn, C
dc.contributor.authorBeyer, R
dc.contributor.authorJeon, S
dc.contributor.authorCho, YS
dc.contributor.authorHofreiter, M
dc.contributor.authorBhak, J
dc.contributor.authorManica, A
dc.contributor.authorPinhasi, R
dc.contributor.orcidEriksson, Anders [0000-0003-3436-3726]
dc.contributor.orcidManica, Andrea [0000-0003-1895-450X]
dc.date.accessioned2018-10-18T10:20:35Z
dc.date.available2018-10-18T10:20:35Z
dc.date.issued2016-08-09
dc.description.abstractThe agricultural transition profoundly changed human societies. We sequenced and analysed the first genome (1.39x) of an early Neolithic woman from Ganj Dareh, in the Zagros Mountains of Iran, a site with early evidence for an economy based on goat herding, ca. 10,000 BP. We show that Western Iran was inhabited by a population genetically most similar to hunter-gatherers from the Caucasus, but distinct from the Neolithic Anatolian people who later brought food production into Europe. The inhabitants of Ganj Dareh made little direct genetic contribution to modern European populations, suggesting those of the Central Zagros were somewhat isolated from other populations of the Fertile Crescent. Runs of homozygosity are of a similar length to those from Neolithic farmers, and shorter than those of Caucasus and Western Hunter-Gatherers, suggesting that the inhabitants of Ganj Dareh did not undergo the large population bottleneck suffered by their northern neighbours. While some degree of cultural diffusion between Anatolia, Western Iran and other neighbouring regions is possible, the genetic dissimilarity between early Anatolian farmers and the inhabitants of Ganj Dareh supports a model in which Neolithic societies in these areas were distinct.
dc.format.mediumElectronic
dc.identifier.doi10.17863/CAM.31470
dc.identifier.eissn2045-2322
dc.identifier.issn2045-2322
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/284099
dc.languageeng
dc.language.isoeng
dc.publisherSpringer Science and Business Media LLC
dc.publisher.urlhttp://dx.doi.org/10.1038/srep31326
dc.rightsAttribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectAgriculture
dc.subjectArchaeology
dc.subjectDNA, Ancient
dc.subjectDNA, Mitochondrial
dc.subjectEthnicity
dc.subjectEurope
dc.subjectFarmers
dc.subjectFemale
dc.subjectGenetic Variation
dc.subjectGenetics, Population
dc.subjectGenome, Human
dc.subjectGeography
dc.subjectHaplotypes
dc.subjectHuman Migration
dc.subjectHumans
dc.subjectIran
dc.subjectPhenotype
dc.subjectPhylogeny
dc.subjectPrincipal Component Analysis
dc.titleThe genetics of an early Neolithic pastoralist from the Zagros, Iran.
dc.typeArticle
dcterms.dateAccepted2016-07-15
prism.publicationDate2016
prism.publicationNameSci Rep
prism.startingPage31326
prism.volume6
pubs.funder-project-idEuropean Research Council (647787)
pubs.funder-project-idEuropean Research Council (617627)
rioxxterms.licenseref.startdate2016-08-09
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/
rioxxterms.typeJournal Article/Review
rioxxterms.versionVoR
rioxxterms.versionofrecord10.1038/srep31326

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