Research data supporting "A Novel Methodology for the Incorporation of Chiral Linkers in Stapled Peptides"
Repository URI
Repository DOI
Change log
Authors
Serrano, Juan C. https://orcid.org/0000-0002-3671-3809
Sipthorp, James
Xu, Wenshu
Itzhaki, Laura
Ley, Steven V.
Description
This file contains organic compound characterisation data and peptide characterisation data for the project "A Novel Methodology for the Incorporation of Chiral Linkers in Stapled Peptides" Organic Data: ChemDraw Structure, NMR, IR, HRMS, and HPLC data (if applicable) of compounds 1-9 Peptide Data: HPLC purity, HRMS, Circular Dichroism, proteolytic assay, and fluorescence polarisation assay data for all purified peptides.
Version
Software / Usage instructions
ChemDraw OpenChrom (for .D HPLC files; other programs applicable) AdobeReader MestReNova Microsoft Excel
Keywords
stapled peptide, two-component stapling, protein-protein interactions, solid-phase synthesis
Publisher
University of Cambridge
Sponsorship
EPSRC [EP/K009494/1, EP/M004120/1 and EP/K/039520/1], Gates-Cambridge Trust