Extended-spectrum β-lactamase-producing and carbapenemase-producing Enterobacteriaceae.
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Peer-reviewed
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Abstract
Antimicrobial resistance (AMR) is a global public-health emergency, which threatens the advances made by modern medical care over the past century. The World Health Organization has recently published a global priority list of antibiotic-resistant bacteria, which includes extended-spectrum β-lactamase-producing Enterobacteriaceae and carbapenemase-producing Enterobacteriaceae. In this review, we highlight the mechanisms of resistance and the genomic epidemiology of these organisms, and the impact of AMR.
Description
Keywords
CPE, ESBL, Enterobacteriaceae, Gram-negative, antimicrobial resistance, Anti-Bacterial Agents, Antimicrobial Stewardship, Bacterial Proteins, Carbapenem-Resistant Enterobacteriaceae, Drug Resistance, Multiple, Bacterial, Enterobacteriaceae, Enterobacteriaceae Infections, Genes, Bacterial, Humans, Molecular Epidemiology, Prevalence, Whole Genome Sequencing, beta-Lactamases
Journal Title
Microb Genom
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Journal ISSN
2057-5858
2057-5858
2057-5858
Volume Title
4
Publisher
Microbiology Society
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Except where otherwised noted, this item's license is described as Attribution 4.0 International
Sponsorship
Academy of Medical Sciences (unknown)
Medical Research Council (MR/N029399/1)
Medical Research Council (MR/N029399/1)
The Academy of Medical Sciences, the Health Foundation, and the NIHR Cambridge Biomedical Research Centre.