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Epithelioid haemangioendothelioma—a rare cause of right pleural effusion and multiple primary nodules: Case report & review of the literature

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Bashir Mohamed, Ryan; orcid: 0000-0002-1005-6433; email: 
Shehata, Monica 
Gorman, William; orcid: 0000-0003-3509-7650 
AlShammari, Abdullah 
Buderi, Silviu 


Pulmonary epithelioid haemangioendothelioma (PEH) is a rare vascular neoplasm. The thoracic manifestation of this disorder is identified via three major imaging patterns, namely multiple primary nodules, diffuse infiltrative pleural thickening, and multiple pulmonary reticulonodular opacities. The commonest pattern of presentation is bilateral multiple nodules. Diagnosis is based on histopathological findings and verified by positive immunochemistry staining. Patients with PEH are usually asymptomatic. We report the case of a 51-year-old female who presented to our facility with a five-month history of cough, pleural nodularity, and pleural effusion. She underwent surgical washout with right pleural biopsies that showed a malignant epithelioid tumor with features of epithelioid haemangioendothelioma (EH). A CXR after treatment did not demonstrate a residual pleural effusion.


Peer reviewed: True


literature review, Epithelioid haemangioendothelioma, case report

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SAGE Publications