Molecular insights into vascular aging.
cam.issuedOnline | 2018-12-05 | |
dc.contributor.author | Foote, Kirsty | |
dc.contributor.author | Bennett, Martin R | |
dc.contributor.orcid | Bennett, Martin [0000-0002-2565-1825] | |
dc.date.accessioned | 2019-02-08T11:51:23Z | |
dc.date.available | 2019-02-08T11:51:23Z | |
dc.date.issued | 2018-12-05 | |
dc.description.abstract | Aging of the vasculature is the leading risk factor for cardiovascular and cerebrovascular disease [1]. As such, strategies that delay vascular aging could minimize the risk of developing life-threatening vascular complications, enhance healthspan and prolong lifespan. However, such preventative and therapeutic approaches require identification of the pathophysiological changes underlying vascular aging, and the associated molecular mechanisms responsible. | |
dc.description.sponsorship | This work was supported by Briitsh Heart Foundation grants BHF) grants PG/13/25/30014, PG/14/69/31032, PG/16/63/32307 and RG/13/14/30314, the National Institute for Health Research Cambridge Biomedical Research Centre, the BHF Centre for Research Excellence, | |
dc.format.medium | ||
dc.identifier.doi | 10.17863/CAM.36287 | |
dc.identifier.eissn | 1945-4589 | |
dc.identifier.issn | 1945-4589 | |
dc.identifier.uri | https://www.repository.cam.ac.uk/handle/1810/289025 | |
dc.language | eng | |
dc.language.iso | eng | |
dc.publisher | Impact Journals, LLC | |
dc.publisher.url | http://dx.doi.org/10.18632/aging.101697 | |
dc.rights | Attribution 4.0 International | |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
dc.subject | aging | |
dc.subject | mitochondria | |
dc.subject | vascular stiffness | |
dc.subject | Age Factors | |
dc.subject | Aging | |
dc.subject | Animals | |
dc.subject | Arteries | |
dc.subject | Gene Expression Regulation | |
dc.subject | Genetic Markers | |
dc.subject | Humans | |
dc.subject | Signal Transduction | |
dc.subject | Vascular Diseases | |
dc.subject | Vascular Remodeling | |
dc.subject | Vascular Stiffness | |
dc.title | Molecular insights into vascular aging. | |
dc.type | Article | |
dcterms.dateAccepted | 2018-11-29 | |
prism.endingPage | 3649 | |
prism.issueIdentifier | 12 | |
prism.publicationDate | 2018 | |
prism.publicationName | Aging (Albany NY) | |
prism.startingPage | 3647 | |
prism.volume | 10 | |
pubs.funder-project-id | British Heart Foundation (CH/2000003) | |
pubs.funder-project-id | British Heart Foundation (None) | |
pubs.funder-project-id | British Heart Foundation (PG/16/63/32307) | |
pubs.funder-project-id | British Heart Foundation (PG/16/11/32021) | |
pubs.funder-project-id | British Heart Foundation (PG/16/24/32090) | |
pubs.funder-project-id | British Heart Foundation (None) | |
pubs.funder-project-id | British Heart Foundation (None) | |
rioxxterms.licenseref.startdate | 2018-12 | |
rioxxterms.licenseref.uri | http://creativecommons.org/licenses/by/4.0/ | |
rioxxterms.type | Journal Article/Review | |
rioxxterms.version | VoR | |
rioxxterms.versionofrecord | 10.18632/aging.101697 |
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