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Technical recommendations for clinical translation of renal MRI: a consensus project of the Cooperation in Science and Technology Action PARENCHIMA.

Published version
Peer-reviewed

Change log

Authors

Mendichovszky, Iosif 
Pullens, Pim 
Dekkers, Ilona 
Nery, Fabio 
Bane, Octavia 

Abstract

PURPOSE: The potential of renal MRI biomarkers has been increasingly recognised, but clinical translation requires more standardisation. The PARENCHIMA consensus project aims to develop and apply a process for generating technical recommendations on renal MRI. METHODS: A task force was formed in July 2018 focused on five methods. A draft process for attaining consensus was distributed publicly for consultation and finalised at an open meeting (Prague, October 2018). Four expert panels completed surveys between October 2018 and March 2019, discussed results and refined the surveys at a face-to-face meeting (Aarhus, March 2019) and completed a second round (May 2019). RESULTS: A seven-stage process was defined: (1) formation of expert panels; (2) definition of the context of use; (3) literature review; (4) collection and comparison of MRI protocols; (5) consensus generation by an approximate Delphi method; (6) reporting of results in vendor-neutral and vendor-specific terms; (7) ongoing review and updating. Application of the process resulted in 166 consensus statements. CONCLUSION: The process generated meaningful technical recommendations across very different MRI methods, while allowing for improvement and refinement as open issues are resolved. The results are likely to be widely supported by the renal MRI community and thereby promote more harmonisation.

Description

Keywords

Biomarkers, Consensus, Imaging, Kidney, Standardisation, Biomarkers, Consensus, Delphi Technique, Europe, Expert Testimony, Humans, Image Processing, Computer-Assisted, Kidney, Magnetic Resonance Imaging, Nephrology, Reference Standards, Surveys and Questionnaires, Translational Research, Biomedical, United States

Journal Title

MAGMA

Conference Name

Journal ISSN

0968-5243
1352-8661

Volume Title

Publisher

Springer Science and Business Media LLC
Sponsorship
Medical Research Council (MR/R02264X/1)