Protein-Protein Conjugates: Tyrosine Delivers.
Accepted version
Peer-reviewed
Repository URI
Repository DOI
Change log
Authors
Geeson, Michael B
Bernardes, Gonçalo JL
Abstract
The residues cysteine and lysine are the undisputed champions of bioconjugation chemistry. Targeting other amino acids has been touted as a potential way to improve the synthesis of protein–peptide and protein–protein conjugates that are widely studied for their potential therapeutic ability and used as tools for understanding biological function. Now, a team of researchers at the University of California, Berkeley, have targeted solvent-exposed tyrosine residues to develop a method of preparing such conjugates.
Description
Keywords
34 Chemical Sciences, Biotechnology, 5.1 Pharmaceuticals, Generic health relevance
Journal Title
ACS Cent Sci
Conference Name
Journal ISSN
2374-7943
2374-7951
2374-7951
Volume Title
6
Publisher
American Chemical Society (ACS)
Publisher DOI
Rights
All rights reserved