Repository logo
 

Protein-Protein Conjugates: Tyrosine Delivers.

Accepted version
Peer-reviewed

Type

Article

Change log

Authors

Geeson, Michael B 
Bernardes, Gonçalo JL 

Abstract

The residues cysteine and lysine are the undisputed champions of bioconjugation chemistry. Targeting other amino acids has been touted as a potential way to improve the synthesis of protein–peptide and protein–protein conjugates that are widely studied for their potential therapeutic ability and used as tools for understanding biological function. Now, a team of researchers at the University of California, Berkeley, have targeted solvent-exposed tyrosine residues to develop a method of preparing such conjugates.

Description

Keywords

34 Chemical Sciences, Biotechnology, 5.1 Pharmaceuticals, Generic health relevance

Journal Title

ACS Cent Sci

Conference Name

Journal ISSN

2374-7943
2374-7951

Volume Title

6

Publisher

American Chemical Society (ACS)

Rights

All rights reserved