Embryonic Inversion in Volvox carteri: The Flipping and Peeling of Elastic Lips.


Type
Article
Change log
Authors
Haas, Pierre A 
Goldstein, Raymond E 
Abstract

The embryos of the green alga Volvox carteri are spherical sheets of cells that turn themselves inside out at the close of their development through a programme of cell shape changes. This process of inversion is a model for morphogenetic cell sheet deformations; it starts with four lips opening up at the anterior pole of the cell sheet, flipping over and peeling back to invert the embryo. Experimental studies have revealed that inversion is arrested if some of these cell shape changes are inhibited, but the mechanical basis for these observations has remained unclear. Here, we analyse the mechanics of this inversion by deriving an averaged elastic theory for these lips and we interpret the experimental observations in terms of the mechanics and evolution of inversion.

Description
Keywords
40 Engineering, Generic health relevance
Journal Title
Phys Rev E
Conference Name
Journal ISSN
2470-0045
2470-0053
Volume Title
98
Publisher
American Physical Society (APS)
Sponsorship
Engineering and Physical Sciences Research Council (EP/M017982/1)
Wellcome Trust (207510/Z/17/Z)
We ... are grateful for support from the Engineering and Physical Sciences Research Council (Established Career Fellowship EP/M017982/1, REG; Doctoral Prize Fellowship, PAH), the Schlumberger Chair Fund, the Wellcome Trust (Investigator Award 207510/Z/17/Z, REG) and Magdalene College, Cambridge (Nevile Research Fellowship, PAH).