Since the 1970s 'hybrid seeds' have been linked to many perceived perils of industrialized agriculture. This essay revisits the scholarship that helped produce a dominant critical assessment of hybrid seeds, situating its emergence in a series of events and interventions of the late twentieth century. It explores how the singular history of F1 hybrid corn inflected understandings of crop breeding and seed production in general, contributing to effective political mobilization against agroindustry as well as lasting confusion about the promises and pitfalls of distinct approaches to crop development and the nature of hybrid seeds.