Discovery and characterisation of driver mutations in liver disease

Discovery and characterisation of driver mutations in liver disease

Repository URI

https://www.repository.cam.ac.uk/handle/1810/374820

Repository DOI

https://doi.org/10.17863/CAM.112735

Type

Authors

Brzozowska, Natalia

Abstract

[Restricted]

Date

2024-04-30

Advisors

Campbell, Peter
Hoare, Matthew

Keywords

alpha-1-antitrypsin deficiency, chronic liver disease, cirrhosis, driver landscape, genomics, insulin resistance, liver, multiomics, obesity, somatic mutations, spatial transcriptomics, steatotic liver disease

Qualification

Doctor of Philosophy (PhD)

Awarding Institution

University of Cambridge

Rights and licensing

All Rights Reserved

Except where otherwised noted, this item's license is described as All Rights Reserved

Relationships

Is supplemented by:

https://doi.org/10.17632/283gy325fk.1
https://doi.org/10.1038/s41586-021-03974-6

Collections

Theses - Wellcome Sanger Institute