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Mortality associated with clozapine: what is the evidence?

Accepted version
Peer-reviewed

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Article

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Authors

Fernandez-Egea, Emilio 
Flanagan, Robert J 
Taylor, David 
Gaughran, Fiona 
Lawrie, Stephen M 

Abstract

It is undeniable that clozapine can lead to fatal outcomes if its toxic effects are not promptly identified and managed. Whilst acknowledging the risks associated with clozapine risks, media reports can overestimate the number of fatal outcomes due to clozapine. Such reports can alarm patients and their relatives and may prompt patients prescribed clozapine to discontinue their treatment and thus prevent them from using the best medication for the most difficult-to-treat psychosis thereby increasing their risk of relapse.

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Journal Title

British journal of Psychiatry

Conference Name

Journal ISSN

0007-1250
1472-1465

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Sponsorship
MRC (MR/W029987/1)