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Genetically proxied interleukin-6 receptor inhibition: opposing associations with COVID-19 and pneumonia.

Accepted version
Peer-reviewed

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Type

Article

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Authors

Burgess, Stephen 
Gill, Dipender 

Abstract

Respiratory disease is a main feature of severe COVID-19, and the potential of IL-6 receptor blockade to increase risk of pneumonia warrants vigilance and caution in its application to treat COVID-19 https://bit.ly/34Y8Ner

Description

Keywords

C-Reactive Protein, COVID-19, Genetic Predisposition to Disease, Hospitalization, Humans, Mendelian Randomization Analysis, Pneumonia, Polymorphism, Single Nucleotide, Receptors, Interleukin-6, Respiratory Insufficiency, SARS-CoV-2, Severity of Illness Index, White People, COVID-19 Drug Treatment

Journal Title

Eur Respir J

Conference Name

Journal ISSN

0903-1936
1399-3003

Volume Title

57

Publisher

European Respiratory Society (ERS)

Rights

All rights reserved
Sponsorship
Wellcome Trust (204623/Z/16/Z)
Medical Research Council (MC_UU_00002/7)