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A cross-sectional MR study of body fat volumes and distribution in chronic schizophrenia

Published version
Peer-reviewed

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Authors

Brugger, Stefan P. 
Howes, Oliver D. 

Abstract

Abstract: People with schizophrenia show higher risk for abdominal obesity than the general population, which could contribute to excess mortality. However, it is unclear whether this is driven by alterations in abdominal fat partitioning. Here, we test the hypothesis that individuals with schizophrenia show a higher proportion of visceral to total body fat measured using magnetic resonance imaging (MRI). We recruited 38 participants with schizophrenia and 38 healthy controls matched on age, sex, ethnicity, and body mass index. We found no significant differences in body fat distribution between groups, suggesting that increased abdominal obesity in schizophrenia is not associated with altered fat distribution.

Description

Funder: DH | National Institute for Health Research (NIHR); doi: https://doi.org/10.13039/501100000272


Funder: RCUK | Medical Research Council (MRC); doi: https://doi.org/10.13039/501100000265

Keywords

Brief Communication, /631/378/340, /692/699/476/1799, brief-communication

Journal Title

Schizophrenia

Conference Name

Journal ISSN

2754-6993

Volume Title

8

Publisher

Nature Publishing Group UK