AHRQ series on complex intervention systematic reviews-paper 5: advanced analytic methods.


Type
Article
Change log
Authors
Pigott, Terri 
Noyes, Jane 
Umscheid, Craig A 
Myers, Evan 
Morton, Sally C 
Abstract

BACKGROUND AND OBJECTIVE: Advanced analytic methods for synthesizing evidence about complex interventions continue to be developed. In this paper, we emphasize that the specific research question posed in the review should be used as a guide for choosing the appropriate analytic method. METHODS: We present advanced analytic approaches that address four common questions that guide reviews of complex interventions: (1) How effective is the intervention? (2) For whom does the intervention work and in what contexts? (3) What happens when the intervention is implemented? and (4) What decisions are possible given the results of the synthesis? CONCLUSION: The analytic approaches presented in this paper are particularly useful when each primary study differs in components, mechanisms of action, context, implementation, timing, and many other domains.

Description
Keywords
Bayesian analysis, Decision analysis, Finite mixture models, Meta-analysis, Meta-regression, Qualitative synthesis, Systematic review, Bayes Theorem, Decision Making, Evidence-Based Medicine, Finite Element Analysis, Guidelines as Topic, Humans, Meta-Analysis as Topic, Qualitative Research, Research Design, Review Literature as Topic
Journal Title
J Clin Epidemiol
Conference Name
Journal ISSN
0895-4356
1878-5921
Volume Title
90
Publisher
Elsevier BV