UK clinical guideline for the prevention and treatment of osteoporosis.


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Authors
Gregson, Celia L 
Armstrong, David J 
Bowden, Jean 
Cooper, Cyrus 
Edwards, John 
Abstract

UNLABELLED: The National Osteoporosis Guideline Group (NOGG) has revised the UK guideline for the assessment and management of osteoporosis and the prevention of fragility fractures in postmenopausal women, and men age 50 years and older. Accredited by NICE, this guideline is relevant for all healthcare professionals involved in osteoporosis management. INTRODUCTION: The UK National Osteoporosis Guideline Group (NOGG) first produced a guideline on the prevention and treatment of osteoporosis in 2008, with updates in 2013 and 2017. This paper presents a major update of the guideline, the scope of which is to review the assessment and management of osteoporosis and the prevention of fragility fractures in postmenopausal women, and men age 50 years and older. METHODS: Where available, systematic reviews, meta-analyses and randomised controlled trials were used to provide the evidence base. Conclusions and recommendations were systematically graded according to the strength of the available evidence. RESULTS: Review of the evidence and recommendations are provided for the diagnosis of osteoporosis, fracture-risk assessment and intervention thresholds, management of vertebral fractures, non-pharmacological and pharmacological treatments, including duration and monitoring of anti-resorptive therapy, glucocorticoid-induced osteoporosis, and models of care for fracture prevention. Recommendations are made for training; service leads and commissioners of healthcare; and for review criteria for audit and quality improvement. CONCLUSION: The guideline, which has received accreditation from the National Institute of Health and Care Excellence (NICE), provides a comprehensive overview of the assessment and management of osteoporosis for all healthcare professionals involved in its management. This position paper has been endorsed by the International Osteoporosis Foundation and by the European Society for the Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases.

Description

Acknowledgements: NOGG are grateful to our external peer reviewers, stakeholders, and the Committee of Scientific Advisors of the International Osteoporosis Foundation and by the European Society for the Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases for their endorsement of this manuscript.

Keywords
Fracture, Guideline, NOGG, Osteoporosis, Bone Density, Female, Fractures, Bone, Humans, Male, Middle Aged, Osteoporosis, Risk Assessment, United Kingdom
Journal Title
Arch Osteoporos
Conference Name
Journal ISSN
1862-3522
1862-3514
Volume Title
Publisher
Springer Science and Business Media LLC
Sponsorship
National Institute for Health Research (CS-2018-18-ST2-010)