Estimating the burden of SARS-CoV-2 in France (vol 368, eabd4246, 2020)


Type
Article
Change log
Authors
Kiem, Cecile Tran 
Courtejoie, Noemie 
Bosetti, Paolo 
Abstract

France has been heavily affected by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic and went into lockdown on 17 March 2020. Using models applied to hospital and death data, we estimate the impact of the lockdown and current population immunity. We find that 2.9% of infected individuals are hospitalized and 0.5% of those infected die (95% credible interval: 0.3 to 0.9%), ranging from 0.001% in those under 20 years of age to 8.3% in those 80 years of age or older. Across all ages, men are more likely to be hospitalized, enter intensive care, and die than women. The lockdown reduced the reproductive number from 2.90 to 0.67 (77% reduction). By 11 May 2020, when interventions are scheduled to be eased, we project that 3.5 million people (range: 2.1 million to 6.0 million), or 5.3% of the population (range: 3.3 to 9.3%), will have been infected. Population immunity appears to be insufficient to avoid a second wave if all control measures are released at the end of the lockdown.

Description
Keywords
Adolescent, Adult, Aged, Aged, 80 and over, COVID-19, Coronavirus Infections, Cost of Illness, Critical Care, Female, France, Hospitalization, Humans, Immunity, Male, Middle Aged, Pandemics, Pneumonia, Viral, Quarantine, Severe acute respiratory syndrome-related coronavirus, Young Adult
Journal Title
Science
Conference Name
Journal ISSN
0036-8075
1095-9203
Volume Title
369
Publisher
American Association for the Advancement of Science
Rights
All rights reserved
Sponsorship
European Commission Horizon 2020 (H2020) ERC (804744)