Recyclable supported Pd-NHC catalytic systems for the copper free Sonogashira cross-coupling in flow
| cam.issuedOnline | 2018-07-06 | |
| dc.contributor.author | Penafiel, Itziar | |
| dc.contributor.author | Martinez-Lombardia, A | |
| dc.contributor.author | Godard, C | |
| dc.contributor.author | Claver, Carmen | |
| dc.contributor.author | Lapkin, AA | |
| dc.contributor.orcid | Lapkin, Alexei [0000-0001-7621-0889] | |
| dc.date.accessioned | 2019-01-11T00:31:26Z | |
| dc.date.available | 2019-01-11T00:31:26Z | |
| dc.date.issued | 2018-09-01 | |
| dc.description.abstract | A new family of well-defined NHC-Pd complexes immobilised onto silica, alumina and titania is reported. The catalysts display activity and recyclability in the Sonogashira cross-coupling reactions under batch and continuous flow conditions. Under batch conditions the new catalytic systems were recycled up to four times with yields over 80%. These catalysts have a broad substrate scope of different aryl bromides and alkynes. The titania-supported catalysts show good conversions under continuous flow conditions at least over 8 hours on stream using MeOH as solvent. | |
| dc.description.sponsorship | The research leading to these results has received funding from the European Research Council under the European Union's Seventh Framework Programme (EC FP7) Grant Agreement n. [NMP2-SL-2012-280827]. The authors are grateful to TECSPR14-1-0045; TECNIOspring programme, the Agency for Business Competitiveness of the Government of Catalonia, ACCIÓ, the Generalitat de Catalunya (2014SGR670). and the Spanish Ministerio de Economía y Competitividad (CTQ2016-75016-R) for financial support. | |
| dc.identifier.doi | 10.17863/CAM.35134 | |
| dc.identifier.issn | 2352-5541 | |
| dc.identifier.uri | https://www.repository.cam.ac.uk/handle/1810/287819 | |
| dc.language.iso | eng | |
| dc.publisher | Elsevier | |
| dc.publisher.url | http://dx.doi.org/10.1016/j.scp.2018.06.003 | |
| dc.subject | 3402 Inorganic Chemistry | |
| dc.subject | 34 Chemical Sciences | |
| dc.title | Recyclable supported Pd-NHC catalytic systems for the copper free Sonogashira cross-coupling in flow | |
| dc.type | Article | |
| dcterms.dateAccepted | 2018-06-27 | |
| prism.endingPage | 75 | |
| prism.publicationDate | 2018 | |
| prism.publicationName | Sustainable Chemistry and Pharmacy | |
| prism.startingPage | 69 | |
| prism.volume | 9 | |
| pubs.funder-project-id | Centre Tecnol�gic de la Qu�mica de Catalunya (CTQC) | |
| rioxxterms.licenseref.startdate | 2018-09-01 | |
| rioxxterms.licenseref.uri | http://www.rioxx.net/licenses/all-rights-reserved | |
| rioxxterms.type | Journal Article/Review | |
| rioxxterms.version | AM | |
| rioxxterms.versionofrecord | 10.1016/j.scp.2018.06.003 |
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