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Practicable assessment of cochlear size and shape from clinical CT images.

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dc.contributor.authorGee, Andrew H
dc.contributor.authorZhao, Yufeng
dc.contributor.authorTreece, Graham M
dc.contributor.authorBance, Manohar L
dc.contributor.orcidTreece, Graham [0000-0003-0047-6845]
dc.date.accessioned2020-07-30T08:54:46Z
dc.date.available2020-07-30T08:54:46Z
dc.date.issued2021-02-10
dc.description.abstractThere is considerable interpersonal variation in the size and shape of the human cochlea, with evident consequences for cochlear implantation. The ability to characterize a specific cochlea, from preoperative computed tomography (CT) images, would allow the clinician to personalize the choice of electrode, surgical approach and postoperative programming. In this study, we present a fast, practicable and freely available method for estimating cochlear size and shape from clinical CT. The approach taken is to fit a template surface to the CT data, using either a statistical shape model or a locally affine deformation (LAD). After fitting, we measure cochlear size, duct length and a novel measure of basal turn non-planarity, which we suggest might correlate with the risk of insertion trauma. Gold-standard measurements from a convenience sample of 18 micro-CT scans are compared with the same quantities estimated from low-resolution, noisy, pseudo-clinical data synthesized from the same micro-CT scans. The best results were obtained using the LAD method, with an expected error of 8-17% of the gold-standard sample range for non-planarity, cochlear size and duct length.
dc.format.mediumElectronic
dc.identifier.doi10.17863/CAM.55677
dc.identifier.eissn2045-2322
dc.identifier.issn2045-2322
dc.identifier.otherARTN 3448
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/308590
dc.language.isoeng
dc.publisherSpringer Science and Business Media LLC
dc.rightsAll Rights Reserved
dc.rights.urihttps://www.rioxx.net/licenses/all-rights-reserved/
dc.subjectCochlea
dc.subjectCochlear Implantation
dc.subjectCochlear Implants
dc.subjectHumans
dc.subjectOrgan Size
dc.subjectTemporal Bone
dc.subjectTomography, X-Ray Computed
dc.titlePracticable assessment of cochlear size and shape from clinical CT images.
dc.typeReport
dcterms.formatElectronic
prism.publicationDate2021
prism.startingPage3448
rioxxterms.licenseref.startdate2021-02-10
rioxxterms.licenseref.urihttps://www.rioxx.net/licenses/all-rights-reserved/
rioxxterms.typeTechnical Report
rioxxterms.versionofrecord10.1038/s41598-021-83059-6

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