Repository logo
 

Seroprevalence of anti-SARS-CoV-2 IgG at the first epidemic peak in French Guiana, July 2020.

Simple item page
cam.issuedOnline2021-11-12
datacite.contributor.supervisoreditor: Bowman, Natalie
dc.contributor.authorFlamand, Claude
dc.contributor.authorAlves Sarmento, Christelle
dc.contributor.authorEnfissi, Antoine
dc.contributor.authorBailly, Sarah
dc.contributor.authorBeillard, Emmanuel
dc.contributor.authorGaillet, Mélanie
dc.contributor.authorMichaud, Céline
dc.contributor.authorServas, Véronique
dc.contributor.authorClement, Nathalie
dc.contributor.authorPerilhou, Anaïs
dc.contributor.authorCarage, Thierry
dc.contributor.authorMusso, Didier
dc.contributor.authorCarod, Jean-François
dc.contributor.authorEustache, Stéphanie
dc.contributor.authorTourbillon, Céline
dc.contributor.authorBoizon, Elodie
dc.contributor.authorJames, Samantha
dc.contributor.authorDjossou, Félix
dc.contributor.authorSalje, Henrik
dc.contributor.authorCauchemez, Simon
dc.contributor.authorRousset, Dominique
dc.contributor.orcidFlamand, Claude [0000-0002-8064-445X]
dc.contributor.orcidBeillard, Emmanuel [0000-0002-2546-7614]
dc.contributor.orcidMichaud, Céline [0000-0001-5410-6298]
dc.contributor.orcidSalje, Henrik [0000-0003-3626-4254]
dc.contributor.orcidCauchemez, Simon [0000-0001-9186-4549]
dc.date.accessioned2021-12-22T15:05:19Z
dc.date.available2021-12-22T15:05:19Z
dc.date.issued2021-11
dc.date.submitted2020-10-12
dc.date.updated2021-12-22T15:05:18Z
dc.descriptionFunder: National Research Agency
dc.descriptionFunder: Regional Health Agency of French Guiana
dc.descriptionFunder: Institut Pasteur Urgence COVID-19 fundraising
dc.description.abstractBACKGROUND: While Latin America has been heavily affected by the pandemic, only a few seroprevalence studies have been conducted there during the first epidemic wave in the first half of 2020. METHODOLOGY/PRINCIPAL FINDINGS: A cross-sectional survey was performed between 15 July 2020 and 23 July 2020 among individuals who visited 4 medical laboratories or 5 health centers for routine screening or clinical management, with the exception of symptomatic suggestive cases of covid-19. Samples were screened for the presence of anti-SARS-CoV-2 IgG directed against domain S1 of the SARS-CoV-2 spike protein using the anti-SARS-CoV-2 enzyme-linked immunosorbent assay (ELISA) from Euroimmun. CONCLUSIONS/SIGNIFICANCE: The overall seroprevalence was 15.4% [9.3%-24.4%] among 480 participants, ranging from 4.0% to 25.5% across the different municipalities. The seroprevalence did not differ according to gender (p = 0.19) or age (p = 0.51). Among SARS-CoV-2 positive individuals, we found that 24.6% [11.5%-45.2%] reported symptoms consistent with COVID-19. Our findings revealed high levels of infection across the territory but a low number of resulting deaths, which can be explained by French Guiana's young population structure.
dc.identifier.doi10.17863/CAM.79136
dc.identifier.eissn1935-2735
dc.identifier.issn1935-2727
dc.identifier.otherpntd-d-20-01805
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/331686
dc.languageen
dc.publisherPublic Library of Science (PLoS)
dc.subjectResearch Article
dc.subjectBiology and life sciences
dc.subjectMedicine and health sciences
dc.subjectResearch and analysis methods
dc.titleSeroprevalence of anti-SARS-CoV-2 IgG at the first epidemic peak in French Guiana, July 2020.
dc.typeArticle
dcterms.dateAccepted2021-10-22
prism.issueIdentifier11
prism.publicationNamePLoS Negl Trop Dis
prism.volume15
pubs.funder-project-idEuropean Regional Development Fund (GY0027257)
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/
rioxxterms.versionVoR
rioxxterms.versionofrecord10.1371/journal.pntd.0009945

Files

Original bundle
Now showing 1 - 3 of 3
No Thumbnail Available
Name:
pntd.0009945.xml
Size:
90.46 KB
Format:
Extensible Markup Language
Description:
Bibliographic metadata
Licence
http://creativecommons.org/licenses/by/4.0/
Download
No Thumbnail Available
Name:
additional-files.zip
Size:
3.71 MB
Format:
ZIP file
Description:
Supporting information
Licence
http://creativecommons.org/licenses/by/4.0/
Download
No Thumbnail Available
Name:
pntd.0009945.pdf
Size:
1.84 MB
Format:
Adobe Portable Document Format
Description:
Published version
Licence
http://creativecommons.org/licenses/by/4.0/
Download

Collections

Jisc Publications Router