Research data supporting "Rapid, selective and stable HaloTag-LbADH immobilization directly from crude cell extract for the continuous biocatalytic production of chiral alcohols and epoxides"
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A strategy for biocatalyst immobilization in flow directly from the crude cell extract is described. The efficiency and the stability of the immobilized enzyme were demonstrated during the asymmetric reduction of a range of ketones. The cascade two-step chemo-enzymatic preparation of chiral epoxides was possible through the initial ketone bioreduction to an intermediate halohydrin followed by its intramolecular cyclization.
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Microsoft Office
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Except where otherwised noted, this item's license is described as Attribution 4.0 International (CC BY 4.0)
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Engineering and Physical Sciences Research Council (EP/K009494/1)