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The evolution of the structure and mechanical properties of fully bioresorbable polymer-glass composites during degradation

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cam.depositDate2021-12-10
cam.issuedOnline2021-12-08
cam.orpheus.success2021-12-17 - Embargo set during processing via Fast-track
datacite.issupplementedby.urlhttps://doi.org/10.17863/CAM.63540
dc.contributor.authorOosterbeek, RN
dc.contributor.authorZhang, XC
dc.contributor.authorBest, SM
dc.contributor.authorCameron, RE
dc.contributor.orcidOosterbeek, RN [0000-0002-2412-4505]
dc.date.accessioned2021-12-18T00:30:14Z
dc.date.available2021-12-18T00:30:14Z
dc.date.issued2022
dc.date.updated2021-12-10T14:05:26Z
dc.description.abstractFully bioresorbable polymer matrix composites have long been considered as potential orthopaedic implant materials, however their combination of mechanical strength, stiffness, ductility and bioresorbability is also attractive for cardiac stent applications. This work investigated reinforcement of polylactide-based polymers with phosphate glasses, addressing key drawbacks of current polymer stents, and examined the often-neglected evolution of structure and mechanical properties during degradation. Incorporation of 15–30wt.% phosphate glass led to modulus increases of up to 80% under simulated body conditions, and 15wt.% glass composites retained comparable ductility to pure polymers, crucial for stent applications where ductility and stiffness are required. Two-stage degradation was observed, dominated by interfacial water absorption and glass dissolution. Polymer embrittlement mechanisms (crystallisation, enthalpy relaxation) were suppressed by glass addition, allowing composites to achieve a more controlled loss of mechanical properties during degradation, which could allow gradual transfer of loading to newly healed tissue. These results provide a valuable new system for understanding the structural and mechanical changes occurring during degradation of fully bioresorbable polymer matrix composites, providing important new data to underpin the design of effective cardiac stent materials.
dc.description.sponsorshipThe authors thank Lucideon Ltd. for providing materials and financial support
dc.identifier.doi10.17863/CAM.79050
dc.identifier.eissn1879-1050
dc.identifier.issn0266-3538
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/331598
dc.language.isoeng
dc.publisherElsevier BV
dc.publisher.departmentDepartment of Materials Science And Metallurgy
dc.publisher.urlhttp://dx.doi.org/10.1016/j.compscitech.2021.109194
dc.rightsAll Rights Reserved
dc.rights.urihttp://www.rioxx.net/licenses/all-rights-reserved
dc.subjectParticle-reinforced composites
dc.subjectPolymer-matrix composites
dc.subjectGlasses
dc.subjectEnvironmental degradation
dc.subjectMechanical properties
dc.titleThe evolution of the structure and mechanical properties of fully bioresorbable polymer-glass composites during degradation
dc.typeArticle
dcterms.dateAccepted2021-12-01
prism.endingPage109194
prism.number109194
prism.publicationDate2021
prism.publicationNameComposites Science and Technology
prism.startingPage109194
pubs.licence-display-nameApollo Repository Deposit Licence Agreement
pubs.licence-identifierapollo-deposit-licence-2-1
rioxxterms.typeJournal Article/Review
rioxxterms.versionAM
rioxxterms.versionofrecord10.1016/j.compscitech.2021.109194

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