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Defining PD subtypes — a step toward personalized management?

Accepted version
Peer-reviewed

Type

Article

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Authors

Williams-Gray, Caroline  ORCID logo  https://orcid.org/0000-0002-2648-9743
Barker, RA 

Abstract

A recent article published in Brain proposes a clinical method for subtyping Parkinson disease cases on an individual basis, with implications for better patient stratification for personalized medicine. The authors report biological validity in terms of imaging and cerebrospinal fluid parameters, but long-term predictive validity remains to be established.

Description

Keywords

biomarkers, Parkinson's disease

Journal Title

Nature Reviews Neurology

Conference Name

Journal ISSN

1759-4758
1759-4766

Volume Title

13

Publisher

Nature Publishing Group
Sponsorship
Parkinson's UK (via Newcastle University) (RES/0168/7579)
Cambridge University Hospitals NHS Foundation Trust (CUH) (146281)
Medical Research Council (MC_PC_12009)
The work of the authors is supported by the NIHR Cambridge Biomedical Research Centre and the Wellcome Trust–Medical Research Council Cambridge Stem Cell Institute.