CLN8 safeguards lysosome biogenesis.
| cam.issuedOnline | 2018-11-05 | |
| dc.contributor.author | Luzio, J Paul | |
| dc.contributor.orcid | Luzio, John [0000-0003-3912-9760] | |
| dc.date.accessioned | 2018-12-13T00:32:50Z | |
| dc.date.available | 2018-12-13T00:32:50Z | |
| dc.date.issued | 2018-12 | |
| dc.description.abstract | Newly synthesised lysosomal proteins are sorted from other cargo on the secretory pathway for delivery to endolysosomal compartments. A study now shows that the Batten disease protein, CLN8, acts as a recycling receptor to sort soluble lysosomal enzymes for export from the endoplasmic reticulum to the Golgi. | |
| dc.format.medium | ||
| dc.identifier.doi | 10.17863/CAM.34157 | |
| dc.identifier.eissn | 1476-4679 | |
| dc.identifier.issn | 1465-7392 | |
| dc.identifier.uri | https://www.repository.cam.ac.uk/handle/1810/286851 | |
| dc.language | eng | |
| dc.language.iso | eng | |
| dc.publisher | Springer Science and Business Media LLC | |
| dc.publisher.url | http://dx.doi.org/10.1038/s41556-018-0240-y | |
| dc.subject | Endoplasmic Reticulum | |
| dc.subject | Endoplasmic Reticulum Stress | |
| dc.subject | Lysosomes | |
| dc.title | CLN8 safeguards lysosome biogenesis. | |
| dc.type | Article | |
| dcterms.dateAccepted | 2018-10-23 | |
| prism.endingPage | 1335 | |
| prism.issueIdentifier | 12 | |
| prism.publicationDate | 2018 | |
| prism.publicationName | Nat Cell Biol | |
| prism.startingPage | 1333 | |
| prism.volume | 20 | |
| rioxxterms.licenseref.startdate | 2018-12 | |
| rioxxterms.licenseref.uri | http://www.rioxx.net/licenses/all-rights-reserved | |
| rioxxterms.type | Journal Article/Review | |
| rioxxterms.version | AM | |
| rioxxterms.versionofrecord | 10.1038/s41556-018-0240-y |
Files
Original bundle
1 - 1 of 1
No Thumbnail Available
- Name:
- Accepted Luzio NewsViews for NCB_Final.docx
- Size:
- 48.39 KB
- Format:
- Microsoft Word XML
- Description:
- Accepted version
- Licence
- http://www.rioxx.net/licenses/all-rights-reserved
License bundle
1 - 1 of 1
No Thumbnail Available
- Name:
- DepositLicenceAgreementv2.1.pdf
- Size:
- 150.9 KB
- Format:
- Adobe Portable Document Format