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Molecular mechanisms of traumatic brain injury: the missing link in management.


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Authors

Veenith, Tonny 
Goon, Serena Sh 
Burnstein, Rowan M 

Abstract

Head injury is common, sometimes requires intensive care unit admission, and is associated with significant mortality and morbidity. A gap still remains in the understanding of the molecular mechanism of this condition. This review is aimed at providing a general overview of the molecular mechanisms involved in traumatic brain injury to a busy clinician. It will encompass the pathophysiology in traumatic brain injury including apoptosis, the role of molecules and genes, and a brief mention of possible pharmacological therapies.

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RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are.

Keywords

32 Biomedical and Clinical Sciences, 3202 Clinical Sciences, Traumatic Brain Injury (TBI), Neurosciences, Physical Injury - Accidents and Adverse Effects, Traumatic Head and Spine Injury, Brain Disorders, 1.1 Normal biological development and functioning, Neurological, 3 Good Health and Well Being

Journal Title

World J Emerg Surg

Conference Name

Journal ISSN

1749-7922
1749-7922

Volume Title

Publisher

Springer Science and Business Media LLC