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A non-coding m6A reader promotes leukaemia.

Accepted version
Peer-reviewed

Type

Article

Change log

Authors

Abstract

Pathways linked to the modification of RNA with N6-methyladenosine (m6A) are known to be involved in initiating and maintaining cancer. But many of the key components of these pathways remain undiscovered. The RBFOX2 protein has now been identified as an m6 A reader involved in locus-specific chromatin regulation, with therapeutic implications for myeloid leukaemia.

Description

Keywords

Cambridge Stem Cells

Journal Title

Nat Cell Biol

Conference Name

Journal ISSN

1465-7392
1476-4679

Volume Title

Publisher

Springer Science and Business Media LLC
Sponsorship
Medical Research Council (MC_PC_17230)