Repository logo
 

Prevalence of Depression and Depressive Symptoms Among Resident Physicians: A Systematic Review and Meta-analysis.

Simple item page
dc.contributor.authorMata, Douglas A
dc.contributor.authorRamos, Marco A
dc.contributor.authorBansal, Narinder
dc.contributor.authorKhan, Rida
dc.contributor.authorGuille, Constance
dc.contributor.authorDi Angelantonio, Emanuele
dc.contributor.authorSen, Srijan
dc.contributor.orcidBansal, Narinder [0000-0002-6925-1719]
dc.contributor.orcidDi Angelantonio, Emanuele [0000-0001-8776-6719]
dc.date.accessioned2018-11-07T00:30:31Z
dc.date.available2018-11-07T00:30:31Z
dc.date.issued2015-12-08
dc.description.abstractIMPORTANCE: Physicians in training are at high risk for depression. However, the estimated prevalence of this disorder varies substantially between studies. OBJECTIVE: To provide a summary estimate of depression or depressive symptom prevalence among resident physicians. DATA SOURCES AND STUDY SELECTION: Systematic search of EMBASE, ERIC, MEDLINE, and PsycINFO for studies with information on the prevalence of depression or depressive symptoms among resident physicians published between January 1963 and September 2015. Studies were eligible for inclusion if they were published in the peer-reviewed literature and used a validated method to assess for depression or depressive symptoms. DATA EXTRACTION AND SYNTHESIS: Information on study characteristics and depression or depressive symptom prevalence was extracted independently by 2 trained investigators. Estimates were pooled using random-effects meta-analysis. Differences by study-level characteristics were estimated using meta-regression. MAIN OUTCOMES AND MEASURES: Point or period prevalence of depression or depressive symptoms as assessed by structured interview or validated questionnaire. RESULTS: Data were extracted from 31 cross-sectional studies (9447 individuals) and 23 longitudinal studies (8113 individuals). Three studies used clinical interviews and 51 used self-report instruments. The overall pooled prevalence of depression or depressive symptoms was 28.8% (4969/17,560 individuals, 95% CI, 25.3%-32.5%), with high between-study heterogeneity (Q = 1247, τ2 = 0.39, I2 = 95.8%, P < .001). Prevalence estimates ranged from 20.9% for the 9-item Patient Health Questionnaire with a cutoff of 10 or more (741/3577 individuals, 95% CI, 17.5%-24.7%, Q = 14.4, τ2 = 0.04, I2 = 79.2%) to 43.2% for the 2-item PRIME-MD (1349/2891 individuals, 95% CI, 37.6%-49.0%, Q = 45.6, τ2 = 0.09, I2 = 84.6%). There was an increased prevalence with increasing calendar year (slope = 0.5% increase per year, adjusted for assessment modality; 95% CI, 0.03%-0.9%, P = .04). In a secondary analysis of 7 longitudinal studies, the median absolute increase in depressive symptoms with the onset of residency training was 15.8% (range, 0.3%-26.3%; relative risk, 4.5). No statistically significant differences were observed between cross-sectional vs longitudinal studies, studies of only interns vs only upper-level residents, or studies of nonsurgical vs both nonsurgical and surgical residents. CONCLUSIONS AND RELEVANCE: In this systematic review, the summary estimate of the prevalence of depression or depressive symptoms among resident physicians was 28.8%, ranging from 20.9% to 43.2% depending on the instrument used, and increased with calendar year. Further research is needed to identify effective strategies for preventing and treating depression among physicians in training.
dc.format.mediumPrint
dc.identifier.doi10.17863/CAM.32056
dc.identifier.eissn1538-3598
dc.identifier.issn0098-7484
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/284683
dc.languageeng
dc.language.isoeng
dc.publisherAmerican Medical Association (AMA)
dc.publisher.urlhttp://dx.doi.org/10.1001/jama.2015.15845
dc.subjectCross-Sectional Studies
dc.subjectDepression
dc.subjectDepressive Disorder
dc.subjectHumans
dc.subjectInternship and Residency
dc.subjectLongitudinal Studies
dc.subjectPrevalence
dc.titlePrevalence of Depression and Depressive Symptoms Among Resident Physicians: A Systematic Review and Meta-analysis.
dc.typeArticle
prism.endingPage2383
prism.issueIdentifier22
prism.publicationDate2015
prism.publicationNameJAMA
prism.startingPage2373
prism.volume314
pubs.funder-project-idMedical Research Council (MR/L003120/1)
pubs.funder-project-idBritish Heart Foundation (None)
rioxxterms.licenseref.startdate2015-12
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.typeJournal Article/Review
rioxxterms.versionAM
rioxxterms.versionofrecord10.1001/jama.2015.15845

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Prevalence of depression.pdf
Size:
1.27 MB
Format:
Adobe Portable Document Format
Description:
Accepted version
Licence
http://www.rioxx.net/licenses/all-rights-reserved
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
DepositLicenceAgreement.pdf
Size:
417.78 KB
Format:
Adobe Portable Document Format
Download

Collections

Cambridge University Research Outputs