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What Have We Learned From the Typhoid Fever Surveillance in Africa Program?

Published version
Peer-reviewed

Type

Article

Change log

Authors

Hombach, Joachim 

Abstract

The Typhoid Fever Surveillance in Africa Program (TSAP) was established in 2009 to fill the data void concerning invasive Salmonella disease in sub-Saharan Africa, and to specifically estimate the burden of bloodstream infections caused by the key pathogen, Salmonella enterica serovar Typhi. TSAP has achieved this ambitious target, finding high incidences of typhoid fever in both rural and urban populations in several countries in sub-Saharan Africa. The results of TSAP will undoubtedly dictate the direction of future typhoid fever research in Africa, and at last provides a key piece of the disease burden jigsaw puzzle. With the dawn of new Vi conjugate vaccines against Salmonella Typhi, the next priority for the typhoid community must be providing the required data on these vaccines so they can be licensed and provided to those in high-risk groups and locations across sub-Saharan Africa.

Description

Keywords

Salmonella Typhi, epidemiology, sub-Saharan Africa, Africa South of the Sahara, Humans, Public Health Surveillance, Salmonella typhi, Typhoid Fever

Journal Title

Clin Infect Dis

Conference Name

Journal ISSN

1058-4838
1537-6591

Volume Title

62 Suppl 1

Publisher

Oxford University Press (OUP)