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dc.contributor.authorBrown, JMen
dc.contributor.authorLansdall, Claireen
dc.contributor.authorWiggins, Jen
dc.contributor.authorDawson, CEen
dc.contributor.authorHunter, Ken
dc.contributor.authorRowe, James Benedicten
dc.contributor.authorParker, RAen
dc.date.accessioned2017-09-22T10:54:15Z
dc.date.available2017-09-22T10:54:15Z
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/267337
dc.description.abstractBACKGROUND: To validate a short cognitive test: the Test Your Memory for Mild Cognitive Impairment (TYM-MCI) in the diagnosis of patients with amnestic mild cognitive impairment or mild Alzheimer’s disease (aMCI/AD). METHODS: Two hundred and two patients with mild memory problems were recruited. All had ‘passed’ the Mini-Mental State Examination (MMSE). Patients completed the TYM-MCI, the Test Your Memory test (TYM), MMSE and revised Addenbrooke’s Cognitive Examination (ACE-R), had a neurological examination, clinical diagnostics and multidisciplinary team review. RESULTS: As a single test, the TYM-MCI performed as well as the ACE-R in the distinction of patients with aMCI/AD from patients with subjective memory impairment with a sensitivity of 0.79 and specificity of 0.91. Used in combination with the ACE-R, it provided additional value and identified almost all cases of aMCI/AD. The TYM-MCI correctly classified most patients who had equivocal ACE-R scores. Integrated discriminant improvement analysis showed that the TYM-MCI added value to the conventional memory assessment. Patients initially diagnosed as unknown or with subjective memory impairment who were later rediagnosed with aMCI/AD scored poorly on their original TYM-MCI. CONCLUSION: The TYM-MCI is a powerful short cognitive test that examines verbal and visual recall and is a valuable addition to the assessment of patients with aMCI/AD. It is simple and cheap to administer and requires minimal staff time and training.
dc.description.sponsorshipJBR was supported by the Wellcome Trust (103838).
dc.publisherBMJ Publishing Group
dc.relation.isreplacedby1810/273230
dc.relation.isreplacedbyhttps://www.repository.cam.ac.uk/handle/1810/273230
dc.rightsAttribution 4.0 Internationalen
dc.rightsAttribution 4.0 Internationalen
dc.rightsAttribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.titleThe Test Your Memory for Mild Cognitive Impairment (TYM-MCI)en
dc.typeArticle
prism.publicationNameJournal of Neurology, Neurosurgery and Psychiatryen
dc.identifier.doi10.17863/CAM.13326
pubs.declined2017-09-20T08:47:24.439+0100
pubs.deleted2017-09-20T08:47:24.439+0100
pubs.merge-to1810/273230
pubs.merge-tohttps://www.repository.cam.ac.uk/handle/1810/273230
dcterms.dateAccepted2017-05-08en
rioxxterms.versionofrecord10.1136/jnnp-2016-315327en
rioxxterms.versionVoR*
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/en
rioxxterms.licenseref.startdate2017-05-08en
dc.contributor.orcidRowe, James Benedict [0000-0001-7216-8679]
rioxxterms.typeJournal Article/Reviewen
pubs.funder-project-idWellcome Trust (103838/Z/14/Z)
cam.issuedOnline2017-09-14en


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Attribution 4.0 International
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