Is It Time to Beta Block the Septic Patient?
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Authors
Pemberton, Philip
Veenith, Tonny
Snelson, Catherine
Whitehouse, Tony
Abstract
Beta blockers are some of the most studied drugs in the pharmacopoeia. They are already widely used in medicine for treating hypertension, chronic heart failure, tachyarrhythmias, and tremor. Whilst their use in the immediate perioperative patient has been questioned, the use of esmolol in the patients with established septic shock has been recently reported to have favourable outcomes. In this paper, we review the role of the adrenergic system in sepsis and the evidence for the use of beta stimulation and beta blockers from animal models to critically ill patients.
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Keywords
Adrenergic beta-Antagonists, Animals, Critical Illness, Humans, Shock, Septic
Journal Title
Biomed Res Int
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Journal ISSN
2314-6133
2314-6141
2314-6141
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Publisher
Hindawi Limited