Show simple item record

dc.contributor.authorDavis, HJen
dc.contributor.authorGenov, Georgien
dc.contributor.authorPhipps, Roberten
dc.date.accessioned2017-11-03T11:19:41Z
dc.date.available2017-11-03T11:19:41Z
dc.date.issued2017-10-16en
dc.identifier.issn1433-7851
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/268067
dc.description.abstractSelective functionalization at the meta position of arenes remains a significant challenge. In this work, we demonstrate that a single anionic bipyridine ligand bearing a remote sulfonate group enables selective iridium-catalyzed borylation of a range of common amine-containing aromatic molecules at the arene meta position. We propose that this selectivity is the result of a key hydrogen bonding interaction between the substrate and catalyst. The scope of this meta-selective borylation is demonstrated on amides derived from benzylamines, phenethylamines and phenylpropylamines; amine-containing building blocks of great utility in many applications.
dc.description.sponsorshipWe are grateful to the EPSRC and Pfizer for a CASE studentship (H.J.D.), the EPSRC (EP/N005422/1, G.R.G.) and the Royal Society for a University Research Fellowship (R.J.P.).
dc.publisherJohn Wiley & Sons Ltd.
dc.rightsAttribution 4.0 International*
dc.rightsAttribution 4.0 Internationalen
dc.rightsAttribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectC-H-Aktivierungen
dc.subjectHomogene Katalyseen
dc.subjectNichtkovalente Wechselwirkungenen
dc.subjectRegioselektivitäten
dc.subjectWasserstoffbrückenen
dc.titlemeta-Selective C−H Borylation of Benzylamine-, Phenethylamine-, and Phenylpropylamine-Derived Amides Enabled by a Single Anionic Liganden
dc.typeArticle
prism.endingPage13540
prism.issueIdentifier43en
prism.publicationDate2017en
prism.publicationNameAngewandte Chemie - International Editionen
prism.startingPage13536
prism.volume129en
dc.identifier.doi10.17863/CAM.14293
dcterms.dateAccepted2017-09-05en
rioxxterms.versionofrecord10.1002/ange.201708967en
rioxxterms.versionVoR*
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/en
rioxxterms.licenseref.startdate2017-10-16en
dc.contributor.orcidGenov, Georgi [0000-0002-8039-3160]
dc.contributor.orcidPhipps, Robert [0000-0002-7383-5469]
dc.identifier.eissn1521-3773
rioxxterms.typeJournal Article/Reviewen
pubs.funder-project-idEPSRC (EP/N005422/1)
pubs.funder-project-idRoyal Society (uf130004)
pubs.funder-project-idEPSRC (1502977)
pubs.funder-project-idEPSRC (EP/K039520/1)
cam.issuedOnline2017-09-06en


Files in this item

Thumbnail
Thumbnail

This item appears in the following Collection(s)

Show simple item record

Attribution 4.0 International
Except where otherwise noted, this item's licence is described as Attribution 4.0 International