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dc.contributor.authorTorsney, KMen
dc.contributor.authorRomero-Ortuno, Romanen
dc.date.accessioned2018-01-09T13:28:04Z
dc.date.available2018-01-09T13:28:04Z
dc.date.issued2018-06en
dc.identifier.issn1478-2715
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/270380
dc.description.abstractBackground: Parkinson’s disease and frailty are both common conditions affecting older people. Little is known regarding the association of the Clinical Frailty Scale with hospital outcomes in idiopathic Parkinson’s disease patients admitted to the acute hospital. We aimed to test whether frailty status was an independent predictor of short-term mortality and other hospital outcomes in older inpatients with idiopathic Parkinson’s disease. Method: We conducted an observational retrospective study in a large tertiary university hospital between October 2014 and October 2016. Routinely measured patient characteristics included demographics (age and sex), Clinical Frailty Scale, acute illness severity (Emergency Department modified Early Warning Score), the Charlson Comorbidity Index, discharge specialty, history of dementia, history of depression and the presence of a new cognitive impairment. Outcomes studied were inpatient mortality, death within 30 days of discharge, new institutionalisation, length of stay ≥7 days and readmission within 30 days to the same hospital. Results: There were 393 first admission episodes of idiopathic Parkinson’s disease patients aged ≥75 years, 166 (42.2%) were female. The mean age (standard deviation) was 82.8 (5.0) years. The mean Clinical Frailty Scale was 5.9 (1.4) and the mean Charlson Comorbidity Index was 1.3 (1.5). After adjustment for covariates, frailty and acute illness severity were independent predictors of inpatient mortality; odds ratio (OR) for severely/very severely frail or terminally ill= 8.1, 95% confidence interval (CI) 1.0-63.5, p=0.045 and OR for acute illness severity: 1.3, 95% CI 1.1-1.6, p=0.005). The CFS did not significantly predict other hospital outcomes. Conclusions: The Clinical Frailty Scale was a significant predictor of inpatient mortality in idiopathic Parkinson’s disease patients admitted to the acute hospital and it might be useful as a marker of risk in this vulnerable population.
dc.format.mediumPrinten
dc.languageengen
dc.publisherRoyal College of Physicians of Edinburgh
dc.subjectHumansen
dc.subjectParkinson Diseaseen
dc.subjectAcute Diseaseen
dc.subjectHospitalizationen
dc.subjectGeriatric Assessmenten
dc.subjectSeverity of Illness Indexen
dc.subjectHospital Mortalityen
dc.subjectRetrospective Studiesen
dc.subjectComorbidityen
dc.subjectAgeden
dc.subjectAged, 80 and overen
dc.subjectFrail Elderlyen
dc.subjectFemaleen
dc.subjectMaleen
dc.subjectFrailtyen
dc.titleThe Clinical Frailty Scale predicts inpatient mortality in older hospitalised patients with idiopathic Parkinson's disease.en
dc.typeArticle
prism.endingPage107
prism.issueIdentifier2en
prism.publicationDate2018en
prism.publicationNameThe journal of the Royal College of Physicians of Edinburghen
prism.startingPage103
prism.volume48en
dc.identifier.doi10.17863/CAM.17252
dcterms.dateAccepted2017-11-28en
rioxxterms.versionofrecord10.4997/jrcpe.2018.201en
rioxxterms.versionAM*
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserveden
rioxxterms.licenseref.startdate2018-06en
dc.contributor.orcidRomero-Ortuno, Roman [0000-0002-3882-7447]
dc.identifier.eissn2042-8189
rioxxterms.typeJournal Article/Reviewen
cam.orpheus.successThu Jan 30 12:59:30 GMT 2020 - The item has an open VoR version.*
rioxxterms.freetoread.startdate2100-01-01


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