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dc.contributor.authorSutton, Stephenen
dc.contributor.authorKinmonth, Ann-Louiseen
dc.contributor.authorHardeman, Wendyen
dc.contributor.authorHughes, Dyfrigen
dc.contributor.authorBoase, Sueen
dc.contributor.authorPrevost, A Tobyen
dc.contributor.authorKellar, Ianen
dc.contributor.authorGraffy, Jonathanen
dc.contributor.authorGriffin, Simonen
dc.contributor.authorFarmer, Andrewen
dc.date.accessioned2018-06-15T11:45:39Z
dc.date.available2018-06-15T11:45:39Z
dc.date.issued2014-12en
dc.identifier.issn0883-6612
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/277087
dc.description.abstractBACKGROUND: Electronic monitoring is recommended for accurate measurement of medication adherence but a possible limitation is that it may influence adherence. PURPOSE: To test the reactive effect of electronic monitoring in a randomized controlled trial. METHODS: A total of 226 adults with type 2 diabetes and HbA1c ≥58 mmol/mol were randomized to receiving their main oral glucose lowering medication in electronic containers or standard packaging. The primary outcomes were self-reported adherence measured with the MARS (Medication Adherence Report Scale; range 5-25) and HbA1c at 8 weeks. RESULTS: Non-significantly higher adherence and lower HbA1c were observed in the electronic container group (differences in means, adjusting for baseline value: MARS, 0.4 [95 % CI -0.1 to 0.8, p = 0.11]; HbA1c (mmol/mol), -1.02 [-2.73 to 0.71, p = 0.25]). CONCLUSIONS: Electronic containers may lead to a small increase in adherence but this potential limitation is outweighed by their advantages. Our findings support electronic monitoring as the method of choice in research on medication adherence. (Trial registration Current Controlled Trials ISRCT N30522359).
dc.format.mediumPrinten
dc.languageengen
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectHumansen
dc.subjectDiabetes Mellitus, Type 2en
dc.subjectHypoglycemic Agentsen
dc.subjectDrug Packagingen
dc.subjectAgeden
dc.subjectMiddle Ageden
dc.subjectFemaleen
dc.subjectMaleen
dc.subjectMedication Adherenceen
dc.subjectElectrical Equipment and Suppliesen
dc.subjectGlycated Hemoglobin Aen
dc.titleDoes electronic monitoring influence adherence to medication? Randomized controlled trial of measurement reactivity.en
dc.typeArticle
prism.endingPage299
prism.issueIdentifier3en
prism.publicationDate2014en
prism.publicationNameAnnals of behavioral medicine : a publication of the Society of Behavioral Medicineen
prism.startingPage293
prism.volume48en
dc.identifier.doi10.17863/CAM.24380
dcterms.dateAccepted2014-01-21en
rioxxterms.versionofrecord10.1007/s12160-014-9595-xen
rioxxterms.versionVoR*
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserveden
rioxxterms.licenseref.startdate2014-12en
dc.contributor.orcidSutton, Stephen [0000-0003-1610-0404]
dc.contributor.orcidHardeman, Wendy [0000-0002-6498-9407]
dc.contributor.orcidHughes, Dyfrig [0000-0001-8247-7459]
dc.contributor.orcidPrevost, A Toby [0000-0003-1723-0796]
dc.contributor.orcidKellar, Ian [0000-0003-1608-5216]
dc.contributor.orcidGriffin, Simon [0000-0002-2157-4797]
dc.identifier.eissn1532-4796
rioxxterms.typeJournal Article/Reviewen
pubs.funder-project-idMRC (G0500267)
pubs.funder-project-idMRC (MC_UU_12015/4)
pubs.funder-project-idNIHR Central Commissioning Facility (NIHRDH-RP-PG-0606-1259)
pubs.funder-project-idMedical Research Council (MC_U106179474)
cam.orpheus.successThu Jan 30 12:59:39 GMT 2020 - The item has an open VoR version.*
rioxxterms.freetoread.startdate2100-01-01


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Attribution 4.0 International
Except where otherwise noted, this item's licence is described as Attribution 4.0 International