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dc.contributor.authorValkovic, Ladislaven
dc.contributor.authorSchmid, Albrecht Ingoen
dc.contributor.authorPurvis, Lucian ABen
dc.contributor.authorEllis, Janeen
dc.contributor.authorNeubauer, Stefanen
dc.contributor.authorRodgers, Christopheren
dc.date.accessioned2018-09-04T09:28:16Z
dc.date.available2018-09-04T09:28:16Z
dc.date.issued2018-06-19en
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/279072
dc.description.abstractSynopsis: Determination of human cardiac Pi using 31P-MRS is challenging as the resonance frequency of Pi is concealed by a close resonating 2,3-DPG signal originating from blood. Long TR acquisition using adiabatic excitation at 7T can compensate for the rapid blood signal replacement in partially-saturated short TR scans. In order to quantify Pi concentration in vivo, knowledge about longitudinal relaxation of Pi is still required. We have measured the T1 of Pi in 4 healthy volunteers at 7T using dual-TR method and used this value to quantify cardiac Pi concentration in 8 healthy volunteers.
dc.description.sponsorshipWe acknowledge financial support from a Sir Henry Dale Fellowship awarded by the Wellcome Trust and the Royal Society (098436/Z/12/Z), and from Slovak Grant Agencies VEGA (2/0001/17) and APVV (15-0029).
dc.publisherThe International Society for Magnetic Resonance in Medicine
dc.titleQuantification of human cardiac inorganic phosphate content in vivo by 31P-MRSI at 7Ten
dc.typeConference Object
prism.number3858en
prism.publicationDate2018en
dc.identifier.doi10.17863/CAM.26454
dcterms.dateAccepted2018-02-02en
rioxxterms.versionAM*
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserveden
rioxxterms.licenseref.startdate2018-06-19en
dc.contributor.orcidRodgers, Christopher [0000-0003-1275-1197]
rioxxterms.typeConference Paper/Proceeding/Abstracten
pubs.funder-project-idWellcome Trust (Unknown)
dc.identifier.urlhttps://www.ismrm.org/18/program_files/EP09.htmen
pubs.conference-nameISMRM 2018en
pubs.conference-start-date2018-06-16en


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