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dc.contributor.authorBourque, Guillaume
dc.contributor.authorBurns, Kathleen H
dc.contributor.authorGehring, Mary
dc.contributor.authorGorbunova, Vera
dc.contributor.authorSeluanov, Andrei
dc.contributor.authorHammell, Molly
dc.contributor.authorImbeault, Michaël
dc.contributor.authorIzsvák, Zsuzsanna
dc.contributor.authorLevin, Henry L
dc.contributor.authorMacfarlan, Todd S
dc.contributor.authorMager, Dixie L
dc.contributor.authorFeschotte, Cédric
dc.date.accessioned2018-11-20T07:03:51Z
dc.date.available2018-11-20T07:03:51Z
dc.date.issued2018-11-19
dc.identifier.citationGenome Biology. 2018 Nov 19;19(1):199
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/285491
dc.description.abstractAbstract Transposable elements (TEs) are major components of eukaryotic genomes. However, the extent of their impact on genome evolution, function, and disease remain a matter of intense interrogation. The rise of genomics and large-scale functional assays has shed new light on the multi-faceted activities of TEs and implies that they should no longer be marginalized. Here, we introduce the fundamental properties of TEs and their complex interactions with their cellular environment, which are crucial to understanding their impact and manifold consequences for organismal biology. While we draw examples primarily from mammalian systems, the core concepts outlined here are relevant to a broad range of organisms.
dc.titleTen things you should know about transposable elements
dc.typeJournal Article
dc.date.updated2018-11-20T07:03:48Z
dc.language.rfc3066en
dc.rights.holderThe Author(s).
dc.identifier.doi10.17863/CAM.32849
rioxxterms.versionofrecord10.1186/s13059-018-1577-z


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