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dc.contributor.authorSharpe, Hayleyen
dc.contributor.authorde Sauvage, Frederic Jen
dc.date.accessioned2019-02-08T09:14:49Z
dc.date.available2019-02-08T09:14:49Z
dc.date.issued2018-02-06en
dc.identifier.issn1937-9145
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/289015
dc.description.abstractThe kinase GRK2 has been linked to the clinically important Hedgehog (HH) signaling pathway, where it is paradoxically required for signal transduction yet also promotes internalization and degradation of the critical HH signal transducer Smoothened. Two reports by Liet aland Pusapatiet alin this issue ofScience Signalingprovide new insights into the role of GRK2 in HH signaling.
dc.languageengen
dc.publisherAmerican Association for the Advancement of Science
dc.titleGrking the Smoothened signal.en
dc.typeArticle
prism.issueIdentifier516en
prism.numbereaar6377en
prism.publicationDate2018en
prism.publicationNameScience signalingen
prism.volume11en
dc.identifier.doi10.17863/CAM.36278
dcterms.dateAccepted2018-01-19en
rioxxterms.versionofrecord10.1126/scisignal.aar6377en
rioxxterms.versionAM*
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserveden
rioxxterms.licenseref.startdate2018-02-06en
dc.contributor.orcidSharpe, Hayley [0000-0002-4723-298X]
dc.identifier.eissn1937-9145
rioxxterms.typeJournal Article/Reviewen
pubs.funder-project-idWELLCOME TRUST (109407/Z/15/Z)
cam.issuedOnline2019-02-06en
dc.identifier.urlhttp://stke.sciencemag.org/content/11/516/eaar6377en


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