Show simple item record

dc.contributor.authorBarrett, Tristanen
dc.contributor.authorKhwaja, Aen
dc.contributor.authorCarmona, Cen
dc.contributor.authorMartinez, Yen
dc.contributor.authorNicholas, Hen
dc.contributor.authorRogers, Gen
dc.contributor.authorWierzbicki, ASen
dc.contributor.authorLewington, AJPen
dc.contributor.authorNICE Chronic Kidney Disease Guideline Development group,en
dc.date.accessioned2020-09-01T23:30:49Z
dc.date.available2020-09-01T23:30:49Z
dc.date.issued2021-03en
dc.identifier.issn0009-9260
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/309827
dc.description.abstractThe National Institute for Health and Care Excellence has recently updated the guideline for “Acute kidney injury: prevention, detection and management” (NG148), providing new recommendations on preventing acute kidney injury (AKI) in adults receiving intravenous iodine-based contrast media. The association between IV iodinated contrast and AKI is controversial, particularly with widespread use of iso-osmolar agents. Associations between contrast administration and AKI are largely based on observational studies, with inherent heterogeneity in patient populations, definitions applied, and timing of laboratory investigations. In an attempt to mitigate risk, kidney protection has typically been employed using IV volume expansion and/or oral acetylcysteine. Such interventions are in widespread use, despite lacking high-quality evidence of benefit. In the non-emergency setting, Glomerular Filtration Rate (GFR) measurements should be obtained within the preceding 3 months before offering IV iodine-based contrast media. In the acute setting, adults should also have their risk of AKI assessed before offering IV iodine-based contrast, however, this should not delay emergency imaging. Based on the evidence available from randomised controlled trials, the NICE committee recommends that oral hydration should be encouraged in adults at increased risk of CI-AKI and that volume expansion with IV fluids should only be considered for inpatients at particularly high risk.
dc.format.mediumPrint-Electronicen
dc.languageengen
dc.publisherElsevier
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectNICE Chronic Kidney Disease Guideline Development groupen
dc.titleAcute kidney injury: prevention, detection, and management. Summary of updated NICE guidance for adults receiving iodine-based contrast media.en
dc.typeArticle
prism.endingPage199
prism.issueIdentifier3en
prism.publicationDate2021en
prism.publicationNameClinical radiologyen
prism.startingPage193
prism.volume76en
dc.identifier.doi10.17863/CAM.56926
dcterms.dateAccepted2020-08-20en
rioxxterms.versionofrecord10.1016/j.crad.2020.08.039en
rioxxterms.versionAM
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserveden
rioxxterms.licenseref.startdate2021-03en
dc.contributor.orcidBarrett, Tristan [0000-0002-1180-1474]
dc.identifier.eissn1365-229X
rioxxterms.typeJournal Article/Reviewen
cam.orpheus.successMon Jan 25 12:07:13 GMT 2021 - Embargo updated*
cam.orpheus.counter22*
rioxxterms.freetoread.startdate2021-12-31


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record

Attribution-NonCommercial-NoDerivatives 4.0 International
Except where otherwise noted, this item's licence is described as Attribution-NonCommercial-NoDerivatives 4.0 International