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dc.contributor.authorYang, Dong
dc.contributor.authorvon Krbek, Larissa KS
dc.contributor.authorYu, Le
dc.contributor.authorRonson, Tanya
dc.contributor.authorThoburn, John D
dc.contributor.authorCarpenter, John P
dc.contributor.authorGreenfield, Jake L
dc.contributor.authorHowe, Duncan J
dc.contributor.authorWu, Biao
dc.contributor.authorNitschke, Jonathan
dc.date.accessioned2020-11-20T00:30:20Z
dc.date.available2020-11-20T00:30:20Z
dc.date.issued2021-02-23
dc.identifier.issn1433-7851
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/313125
dc.description.abstractA bis-urea-functionalized ditopic subcomponent assembled with 2-formylpyridine and FeII , resulting in a dynamic library of metal-organic assemblies: an irregular FeII 4 L6 structure and three FeII 2 L3 stereoisomers: left- and right-handed helicates and a meso-structure. This library reconfigured in response to the addition of monosaccharide derivatives, which served as guests for specific library members, and the rate of saccharide mutarotation was also enhanced by the library. The (P) enantiomer of the FeII 2 L3 helical structure bound β-D-glucose selectively over α-D-glucose. As a consequence, the library collapsed into the (P)-FeII 2 L3 helicate following glucose addition. The α-D-glucose was likewise transformed into the β-D-anomer during equilibration and binding. Thus, β-D-glucose and (P)-3 amplified each other in the product mixture, as metal-organic and saccharide libraries geared together into a single equilibrating system.
dc.description.sponsorshipEuropean Research Council (695009), UK Engineering and Physical Sciences Research Council (EPSRC EP/P027067/1), National Natural Science Foundation of China (No. 21971210), Natural Science Foundation of Shaanxi Province (2019KJXX-062) and the Chinese Scholarship Council (CSC), the Alexander von Humboldt Foundation for a Feodor Lynen Research Fellowship, the Rashkind Family Endowment, the Chenery Endowment, and the Donors of the American Chemical Society Petroleum Research Fund
dc.format.mediumPrint-Electronic
dc.languageeng
dc.publisherWiley
dc.rightsAll rights reserved
dc.titleGlucose Binding Drives Reconfiguration of a Dynamic Library of Urea-Containing Metal-Organic Assemblies.
dc.typeArticle
prism.endingPage4490
prism.issueIdentifier9
prism.publicationDate2021
prism.publicationNameAngew Chem Int Ed Engl
prism.startingPage4485
prism.volume60
dc.identifier.doi10.17863/CAM.60228
dcterms.dateAccepted2020-11-17
rioxxterms.versionofrecord10.1002/anie.202014568
rioxxterms.versionAM
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/
rioxxterms.licenseref.startdate2021-02
dc.contributor.orcidYang, Dong [0000-0002-1971-7349]
dc.contributor.orcidvon Krbek, Larissa KS [0000-0002-4278-5235]
dc.contributor.orcidYu, Le [0000-0002-0360-290X]
dc.contributor.orcidRonson, Tanya [0000-0002-6917-3685]
dc.contributor.orcidCarpenter, John P [0000-0002-4341-2887]
dc.contributor.orcidGreenfield, Jake L [0000-0002-7650-5414]
dc.contributor.orcidWu, Biao [0000-0002-0724-4150]
dc.contributor.orcidNitschke, Jonathan [0000-0002-4060-5122]
dc.identifier.eissn1521-3773
rioxxterms.typeJournal Article/Review
pubs.funder-project-idEuropean Research Council (695009)
pubs.funder-project-idEngineering and Physical Sciences Research Council (EP/P027067/1)
cam.issuedOnline2021-01-07
cam.orpheus.successMon Nov 30 07:30:31 GMT 2020 - Embargo updated
cam.orpheus.counter1
rioxxterms.freetoread.startdate2021-11-20


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