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Cancer development: Origins in the oesophagus.

cam.issuedOnline2017-10-11
dc.contributor.authorZhuang, Lizhe
dc.contributor.authorFitzgerald, Rebecca C
dc.contributor.orcidFitzgerald, Rebecca [0000-0002-3434-3568]
dc.date.accessioned2018-10-22T06:53:51Z
dc.date.available2018-10-22T06:53:51Z
dc.date.issued2017-10-26
dc.description.abstractThe cellular origins of a precancerous condition called Barrett's oesophagus have been unclear. Tracking and analysis of epithelial cells at the affected site could shed light on the problem. See Letter p.529 A precancerous condition called Barrett's oesophagus is of much interest, because it arises when some cells of the oesophagus take on a new identity — a phenomenon known as metaplasia. If we could understand where these altered cells come from, we might hold the key to preventing oesophageal cancer. On page 529, Jiang et al.1 provide fresh insight into the cell of origin for Barrett's oesophagus.
dc.format.mediumPrint-Electronic
dc.identifier.doi10.17863/CAM.31554
dc.identifier.eissn1476-4687
dc.identifier.issn0028-0836
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/284186
dc.languageeng
dc.language.isoeng
dc.publisherSpringer Science and Business Media LLC
dc.publisher.urlhttp://dx.doi.org/10.1038/nature24150
dc.subjectAdenocarcinoma
dc.subjectEsophageal Neoplasms
dc.subjectHumans
dc.titleCancer development: Origins in the oesophagus.
dc.typeArticle
dcterms.dateAccepted2017-10-04
prism.endingPage464
prism.issueIdentifier7677
prism.publicationDate2017
prism.publicationNameNature
prism.startingPage463
prism.volume550
pubs.funder-project-idMedical Research Council (MC_UU_12022/2)
rioxxterms.licenseref.startdate2017-10-11
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.typeJournal Article/Review
rioxxterms.versionAM
rioxxterms.versionofrecord10.1038/nature24150

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