Modern imaging in Cushing's disease.
| cam.depositDate | 2022-06-01 | |
| cam.issuedOnline | 2022-06-06 | |
| cam.orpheus.success | Wed Jun 08 08:57:26 BST 2022 - Embargo updated | |
| dc.contributor.author | Bashari, WA | |
| dc.contributor.author | Gillett, D | |
| dc.contributor.author | MacFarlane, J | |
| dc.contributor.author | Powlson, AS | |
| dc.contributor.author | Kolias, AG | |
| dc.contributor.author | Mannion, R | |
| dc.contributor.author | Scoffings, DJ | |
| dc.contributor.author | Mendichovszky, IA | |
| dc.contributor.author | Jones, J | |
| dc.contributor.author | Cheow, HK | |
| dc.contributor.author | Koulouri, O | |
| dc.contributor.author | Gurnell, M | |
| dc.contributor.orcid | Kolias, Angelos [0000-0003-3992-0587] | |
| dc.contributor.orcid | Gurnell, Mark [0000-0001-5745-6832] | |
| dc.date.accessioned | 2022-06-02T23:30:18Z | |
| dc.date.available | 2022-06-02T23:30:18Z | |
| dc.date.issued | 2022-06-06 | |
| dc.date.updated | 2022-06-01T14:42:17Z | |
| dc.description.abstract | Management of Cushing's disease is informed by dedicated imaging of the sella and parasellar regions. Although magnetic resonance imaging (MRI) remains the investigation of choice, a significant proportion (30-50%) of corticotroph tumours are so small as to render MRI indeterminate or negative when using standard clinical sequences. In this context, alternative MR protocols [e.g. 3D gradient (recalled) echo, with acquisition of volumetric data] may allow detection of tumors that have not been previously visualized. The use of hybrid molecular imaging (e.g. 11C-methionine positron emission tomography coregistered with volumetric MRI) has also been proposed as an additional modality for localizing microadenomas. | |
| dc.identifier.doi | 10.17863/CAM.85100 | |
| dc.identifier.eissn | 1573-7403 | |
| dc.identifier.issn | 1386-341X | |
| dc.identifier.uri | https://www.repository.cam.ac.uk/handle/1810/337694 | |
| dc.language.iso | eng | |
| dc.publisher | Springer Science and Business Media LLC | |
| dc.publisher.department | Department of Medicine | |
| dc.rights | All Rights Reserved | |
| dc.rights.uri | http://www.rioxx.net/licenses/all-rights-reserved | |
| dc.title | Modern imaging in Cushing's disease. | |
| dc.type | Article | |
| dcterms.dateAccepted | 2022-05-19 | |
| prism.publicationName | Pituitary | |
| pubs.funder-project-id | National Institute for Health Research (IS-BRC-1215-20014) | |
| pubs.licence-display-name | Apollo Repository Deposit Licence Agreement | |
| pubs.licence-identifier | apollo-deposit-licence-2-1 | |
| rioxxterms.type | Journal Article/Review | |
| rioxxterms.version | AM | |
| rioxxterms.versionofrecord | 10.1007/s11102-022-01236-w |
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